Who is sponsoring NCT03708159?

NCT03708159 is sponsored by Centre for Addiction and Mental Health.

What drugs are being tested in NCT03708159?

Interventions in NCT03708159: active tDCS + mindfulness meditation, sham tDCS + mindfulness meditation.

What condition does NCT03708159 study?

NCT03708159 studies Major Depressive Disorder.

Is NCT03708159 still recruiting?

NCT03708159 is currently completed. Last updated 20 February 2024.

Last reviewed 2024-02-20 · How we verify

NCT03708159: START

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Maintenance of Response After rTMS for Depression Using tDCS

Completed NA Last updated 20 February 2024

What this trial tests

NA trial testing active tDCS + mindfulness meditation in Major Depressive Disorder in 68 participants. Completed in 31 August 2020.

Timeline

24 September 2018

Primary endpoint
31 August 2020

31 August 2020

Quick facts

Lead sponsor	Centre for Addiction and Mental Health
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	68
Start date	24 September 2018
Primary completion	31 August 2020
Estimated completion	31 August 2020
Sites	2 locations across Canada

Drugs / interventions tested

active tDCS + mindfulness meditation
sham tDCS + mindfulness meditation

Conditions studied

Major Depressive Disorder — all drugs for Major Depressive Disorder →

Sponsor

Centre for Addiction and Mental Health — full company profile →

Who can join

Adults 18 to 85, any sex, with Major Depressive Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a double-blind, multi-site, randomized controlled trial (RCT) that will recruit 200 participants.The purpose of the RCT will be to evaluate the efficacy of transcranial direct current stimulation (tDCS) in combination with mindfulness meditation compared to sham tDCS to maintain wellness following an acute course of repetitive transcranial magnetic stimulation (rTMS) for up to 6 months.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Stimulated brains and meditative minds: A systematic review on combining low intensity transcranial electrical stimulation and meditation in humans.
Divarco R, Ramasawmy P, Petzke F, Antal A. · · 2023 · cited 16× · PMID 36817875 · DOI 10.1016/j.ijchp.2023.100369

Verify or expand the search:

Other recruiting trials for Major Depressive Disorder

Currently open trials in the same condition.

NCT07219394 — Peer-Delivered Behavioral Activation in a CCBHC · NA · recruiting
NCT06705478 — Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disor · Phase 2 · recruiting
NCT06749392 — An Individual-specific Synchrony Signature · NA · recruiting
NCT07316803 — Group Intervention for Romantic Relationships in Young Adults With Severe Mental Illness · NA · recruiting
NCT07242105 — Optimizing Brain Excitability in Depression · NA · recruiting

Other Centre for Addiction and Mental Health trials

Trials by the same sponsor.

NCT07211438 — Evaluating the Role of Psilocybin Monitors in Psilocybin Therapy for Treatment Resistant Depression · Phase 2 · not yet recruiting
NCT07146633 — Efficacy of an EMDR App for PTSD and SUD · NA · recruiting
NCT07228923 — Development and Evaluation of a Theory and Evidence-based Intervention to Reduce Hazardous Alcohol Consumption Among Tre · NA · not yet recruiting
NCT07105449 — THC Titration of High-Potency Cannabis Concentrates · NA · not yet recruiting
NCT06928935 — Digital Dialectical Behavioural Therapy (d-DBT) for Youth at Clinical High Risk (CHR) for Psychosis · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03708159 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre for Addiction and Mental Health
Last refreshed: 20 February 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03708159.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing