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NCT03698136
Electrical Stimulation in Denervated Muscles of the Upper Limbs
NA trial testing Stimulation of denervated muscles in Tetraplegia in 20 participants. Completed in 31 December 2020.
31 December 2020
Quick facts
| Lead sponsor | Swiss Paraplegic Research, Nottwil |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 1 September 2018 |
| Primary completion | 31 December 2020 |
| Estimated completion | 31 December 2020 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Stimulation of denervated muscles
Conditions studied
- Tetraplegia — all drugs for Tetraplegia →
Sponsor
Swiss Paraplegic Research, Nottwil — full company profile →
Who can join
18 and older, any sex, with Tetraplegia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In the last decade the stimulation of denervated muscles got more attention. Not at least because of the promising results of the RISE project (Use of electrical stimulation to restore standing in paraplegics with long-term denervated degenerated muscles). In this European project it was shown that electrical stimulation of denervated muscles in spinal cord injuries (SCI) increased muscle mass and improved the trophic situation of the lower extremities. Furthermore, structural altered muscle into fat- and connective tissue could be restored into contractile muscle tissue by stimulation. However, only a few studies investigated the effect of direct muscle stimulation in case of peripheral nerve damage in the upper extremities. None investigated the stimulation effect in denervated or partially denervated muscles in the upper extremities in tetraplegic patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Electrical stimulation alters muscle morphological properties in denervated upper limb muscles.
Bersch I, Fridén J. · · 2021 · cited 22× · PMID 34896792 · DOI 10.1016/j.ebiom.2021.103737
Verify or expand the search:
- PubMed search for NCT03698136
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Swiss Paraplegic Research, Nottwil trials
Trials by the same sponsor.
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- NCT07165353 — Virtual Walking to Reduce Chronic Neuropathic Pain in Subjects With SCI · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03698136 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Swiss Paraplegic Research, Nottwil
- Last refreshed: 3 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03698136.
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