Last reviewed · How we verify
NCT03694080
Calcium Electroporation for Early Colorectal Cancer
Phase 1 trial testing Calcium electroporation in Colorectal Cancer in 24 participants. Status unknown.
1 May 2020
Quick facts
| Lead sponsor | Zealand University Hospital |
|---|---|
| Phase | Phase 1 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 24 |
| Start date | 1 November 2018 |
| Primary completion | 1 May 2020 |
| Estimated completion | 1 September 2020 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Calcium electroporation — full drug profile →
Conditions studied
- Colorectal Cancer — all drugs for Colorectal Cancer →
Sponsor
Zealand University Hospital
Who can join
18 and older, any sex, with Colorectal Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is an explorative, phase I clinical trial. The aim of this study is to establish the safety and efficacy of treating patients with early colorectal cancer with calcium electroporation prior to intended curative surgery.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
A Comprehensive Review of Calcium Electroporation -A Novel Cancer Treatment Modality.
Frandsen SK, Vissing M, Gehl J. · · 2020 · cited 82× · PMID 31991784 · DOI 10.3390/cancers12020290 -
The Impact of Calcium Overload on Cellular Processes: Exploring Calcicoptosis and Its Therapeutic Potential in Cancer.
Gielecińska A, Kciuk M, Kontek R. · · 2024 · cited 23× · PMID 39769488 · DOI 10.3390/ijms252413727 -
In Vitro Study of Calcium Microsecond Electroporation of Prostate Adenocarcinoma Cells.
Kiełbik A, Szlasa W, Michel O, Szewczyk A, et al · · 2020 · cited 16× · PMID 33227916 · DOI 10.3390/molecules25225406 -
Palliative Treatment of Esophageal Cancer Using Calcium Electroporation.
Egeland C, Baeksgaard L, Gehl J, Gögenur I, et al · · 2022 · cited 14× · PMID 36358702 · DOI 10.3390/cancers14215283
Verify or expand the search:
- PubMed search for NCT03694080
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Calcium electroporation
Trials testing the same drug.
- NCT05609656 — Electroporation and Immunotherapy in Metastatic Colorectal Cancer · Phase 2 · terminated
- NCT04605419 — Calcium Electroporation in Patients With Cell Changes in the Esophagus · Phase 1 · unknown
- NCT04259658 — Histopathologic Effect of Calcium Electroporation on Cancer in the Skin · Phase 2 · completed
- NCT04225767 — Calcium Electroporation as a Treatment for Cutaneous and Subcutaneous Malignant Tumours · Phase 2 · unknown
- NCT03542214 — Calcium Electroporation for the Treatment of Colorectal Cancer · Phase 1 · completed
Other recruiting trials for Colorectal Cancer
Currently open trials in the same condition.
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Other Zealand University Hospital trials
Trials by the same sponsor.
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- NCT07386080 — Carbergoline for Antipsychotic Induced Hyperprolactinemia. · Phase 4 · not yet recruiting
- NCT07482150 — The Connect Trial: Connecting Hospital Patients to Alcohol Care · NA · not yet recruiting
- NCT07460999 — Singing Training vs Usual Care 6-18 Months After Surgical Resection for Non-small Cell Lung Cancer (NSCLC) · NA · recruiting
- NCT07365527 — Sonoporation and Tumor Microenvironment Response in Colorectal Liver Metastases · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03694080 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zealand University Hospital
- Last refreshed: 5 July 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03694080.
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