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NCT03686293: MIGLUCOSE

A Personal Microbiome-dependent Glucose Response in Healthy Young Volunteers

Completed NA Last updated 13 December 2018
What this trial tests

NA trial testing Standardized breakfast in Blood Glucose, High in 31 participants. Completed in 11 December 2018.

Timeline
12 October 2018
Primary endpoint
11 December 2018
11 December 2018

Quick facts

Lead sponsorUniversity of Copenhagen
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposebasic science
Enrollment31
Start date12 October 2018
Primary completion11 December 2018
Estimated completion11 December 2018
Sites1 location across Denmark

Drugs / interventions tested

Conditions studied

Sponsor

University of Copenhagen

Who can join

Adults 18 to 40, any sex, with Blood Glucose, High. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Individuals eating identical meals present high variability in post-meal blood glucose response making comparisons challenging. This study evaluates in 40 healthy and fasted participants whether the postprandial glucose response upon a standardized breakfast is dependent on gut microbial richness. Gastric emptying rate, intestinal transit time, insulin, appetite hormones and measures of the intestinal microbiome and fermentation will also be analyzed in the context of postprandial glucose metabolism.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. The Gut Microbiome and Abiotic Factors as Potential Determinants of Postprandial Glucose Responses: A Single-Arm Meal Study.
    Nestel N, Hvass JD, Bahl MI, Hansen LH, et al · · 2020 · cited 12× · PMID 33585532 · DOI 10.3389/fnut.2020.594850

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Other trials of Standardized breakfast

Trials testing the same drug.

Other University of Copenhagen trials

Trials by the same sponsor.

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