NCT03679104 is a NA clinical trial of Closure of mucosotomy using endoscopic clips in Gastroparesis, sponsored by Institute for Clinical and Experimental Medicine.

Who is sponsoring NCT03679104?

NCT03679104 is sponsored by Institute for Clinical and Experimental Medicine.

What drugs are being tested in NCT03679104?

Interventions in NCT03679104: Closure of mucosotomy using endoscopic clips, Closure of mucosotomy using OverStitch™ suturing device.

What condition does NCT03679104 study?

NCT03679104 studies Gastroparesis.

Is NCT03679104 still recruiting?

NCT03679104 is currently completed. Last updated 27 January 2021.

Last reviewed 2021-01-27 · How we verify

NCT03679104

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Endoscopic Clips Versus Overstich Suturing System Device for Closure of Mucosotomy After G-POEM

Completed NA Last updated 27 January 2021

What this trial tests

NA trial testing Closure of mucosotomy using endoscopic clips in Gastroparesis in 40 participants. Completed in 26 January 2021.

Timeline

1 November 2018

Primary endpoint
1 December 2020

26 January 2021

Quick facts

Lead sponsor	Institute for Clinical and Experimental Medicine
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	treatment
Enrollment	40
Start date	1 November 2018
Primary completion	1 December 2020
Estimated completion	26 January 2021
Sites	1 location across Czechia

Drugs / interventions tested

Closure of mucosotomy using endoscopic clips
Closure of mucosotomy using OverStitch™ suturing device

Conditions studied

Gastroparesis — all drugs for Gastroparesis →

Sponsor

Institute for Clinical and Experimental Medicine

Who can join

Adults 18 to 90, any sex, with Gastroparesis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Gastric per-oral endoscopic pyloromyotomy (G-POEM) has been assessed as new modality for treatment of refractory gastroparesis. G-POEM is promising method, which is still under investigation as its safety and efficacy has not been established yet. The ideal closure technique in patients undergoing G-POEM needs to be established. Several techniques may be used for endoscopic mucosal closure: endoscopic clips, OTSC (over the scope clips), endo-loop based methods (KING closure) or endoscopic suture. The aim of this prospective, open-label study is to compare efficacy and safety of two methods for incision closure in patients who undergo G-POEM: endoscopic clips vs. endoscopic suturing system (OverStitch).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

UEG Week 2019 Poster Presentations.
· 2019 · cited 5× · PMID 32213001 · DOI 10.1177/2050640619854671

Verify or expand the search:

Other recruiting trials for Gastroparesis

Currently open trials in the same condition.

NCT04661215 — Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms · recruiting
NCT07104214 — Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy · recruiting
NCT07526935 — Combined Role of Gastric Peroral Endoscopic Myotomy and Gastric Electrical Stimulator · NA · active not recruiting
NCT05981300 — GpCRC Pediatric Gastroparesis Registry 2 · recruiting
NCT06580197 — The Role of AAT After Abdominal Surgery Based on RWS · recruiting

Other Institute for Clinical and Experimental Medicine trials

Trials by the same sponsor.

NCT07536087 — Endoscopic Ultrasound-Guided Radiofrequency Ablation for Pancreatic Cystic Neoplasms and Pancreatic Neuroendocrine Tumor · NA · recruiting
NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
NCT07326826 — Hernia Repair Using Rectus Fascia Allograft · not yet recruiting
NCT06872255 — Per-oral Endoscopic Myotomy (POEM) in Patients with Postfundplication Dysphagia · NA · not yet recruiting
NCT07153432 — Chronic Kidney Disease Screening · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03679104 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Institute for Clinical and Experimental Medicine
Last refreshed: 27 January 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03679104.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing