Last reviewed · How we verify
NCT03679065
Prophylactic Paracetamol or Dexamethasone for Post-spinal Anesthesia Shivering
Phase 4 trial testing Paracetamol in Shivering in 300 participants. Completed in 31 August 2018.
31 August 2018
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 300 |
| Start date | 1 March 2018 |
| Primary completion | 31 August 2018 |
| Estimated completion | 31 August 2018 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Paracetamol (Paracetamol) — full drug profile →
- Dexamethasone (dexamethasone) — full drug profile →
- Placebo
Conditions studied
- Shivering — all drugs for Shivering →
Sponsor
Ain Shams University
Who can join
Adults 18 to 60, any sex, with Shivering. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study was conducted to evaluate the effects of a prophylactic dose of oral paracetamol on shivering compared with prophylactic intravenous infusion (IVI) dexamethasone in patients undergoing non-obstetric surgeries under spinal anesthesia.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Postspinal anesthesia shivering in lower abdominal and lower limb surgeries: a randomized controlled comparison between paracetamol and dexamethasone.
Esmat IM, Mohamed MM, Abdelaal WA, El-Hariri HM, et al · · 2021 · cited 6× · PMID 34717535 · DOI 10.1186/s12871-021-01483-7
Verify or expand the search:
- PubMed search for NCT03679065
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Paracetamol
Trials testing the same drug.
- NCT07197684 — Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surg · NA · not yet recruiting
- NCT07426744 — Antipyretic Therapy With and Without Cold Sponging · NA · not yet recruiting
- NCT07104097 — Comparison Between 2 Techniques for Lumbar-ESPB · NA · not yet recruiting
- NCT06920056 — A Study of BGM0504 in Overweight or Obese Participants · Phase 1 · completed
- NCT07002788 — Comparison Paravertebral and Serratus Anterior Plane Block in Video-assisted Thoracoscopic Surgery. · NA · active not recruiting
Other recruiting trials for Shivering
Currently open trials in the same condition.
- NCT07511491 — Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Cesarean Section · NA · recruiting
- NCT07489742 — Ondansetron Lozenge Versus Intravenous for Prevention of Shivering in Tonsillectomy · NA · recruiting
- NCT06708169 — Effect of Preemptive Education on the Incidence of Maternal Intraoperative Shivering in Elective Cesarean Delivery · NA · recruiting
- NCT07154849 — Comparative Study Between the Efficacy of Intravenous Hydrocortisone and Intravenous Dexmedetomidine for Prevention of P · Phase 4 · recruiting
- NCT05765162 — Safe Brain Initiative, Operationalizing Precision Anaesthesia · recruiting
Other Ain Shams University trials
Trials by the same sponsor.
- NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
- NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
- NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
- NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03679065 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 20 September 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03679065.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing