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NCT03674593
Clinical and Fundamental Aspects of Prosthetics and Translocation of Mitral Valve Chordae
NA trial testing Mitral valve chordae prosthesis in Degenerative Mitral Valve Disease in 64 participants. Participants enrolled and being followed up; not accepting new ones.
31 December 2025
Quick facts
| Lead sponsor | Tomsk National Research Medical Center of the Russian Academy of Sciences |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 64 |
| Start date | 9 July 2018 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Russia |
Drugs / interventions tested
- Mitral valve chordae prosthesis
- Mitral valve chordae translocation
Conditions studied
- Degenerative Mitral Valve Disease — all drugs for Degenerative Mitral Valve Disease →
Sponsor
Tomsk National Research Medical Center of the Russian Academy of Sciences
Who can join
18 and older, any sex, with Degenerative Mitral Valve Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study compares the efficacies of two surgical procedures for the treatment of mitral valve prolapse due to myxomatous degeneration of the mitral valve: the chordae replacement and the translocation of secondary mitral valve chordae.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03674593
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Degenerative Mitral Valve Disease
Currently open trials in the same condition.
- NCT05655897 — Safety and Efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or · NA · recruiting
- NCT06021509 — Clinical Study of NovoClasp for Treating Moderate to Severe and Severe Degenerative Mitral Regurgitation · NA · active not recruiting
- NCT05595226 — Effect of RT3D-TEE-guided Mitral Valve Repair on Outcomes in Patients With Degenerative Mitral Valve Disease · NA · recruiting
- NCT03706833 — Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial · NA · active not recruiting
Other Tomsk National Research Medical Center of the Russian Academy of Sciences trials
Trials by the same sponsor.
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- NCT07292571 — Evaluation of Different Types of HER2 Expression in Breast Cancer Using [99mTc]Tc -ZHER2:4107 · Phase 2 · enrolling by invitation
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- NCT07018895 — Personalized Hypoxic-hyperoxic Preconditioning in Elderly People · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03674593 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tomsk National Research Medical Center of the Russian Academy of Sciences
- Last refreshed: 9 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03674593.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing