NCT03646097 (Integration-II) is a NA clinical trial of Angio-PCI in Ischaemic Heart Disease, sponsored by Charite University, Berlin, Germany.

Who is sponsoring NCT03646097?

NCT03646097 is sponsored by Charite University, Berlin, Germany.

What drugs are being tested in NCT03646097?

Interventions in NCT03646097: Angio-PCI, OCT-PCI, ACR-PCI.

What condition does NCT03646097 study?

NCT03646097 studies Ischaemic Heart Disease.

Is NCT03646097 still recruiting?

NCT03646097 is currently completed. Last updated 23 April 2019.

Last reviewed 2019-04-23 · How we verify

NCT03646097: Integration-II

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of Real-time Angiographic Co-registered OCT on PCI Results - the OPTICO-integration II Study

Completed NA Last updated 23 April 2019

What this trial tests

NA trial testing Angio-PCI in Ischaemic Heart Disease in 84 participants. Completed in 15 March 2019.

Timeline

21 August 2018

Primary endpoint
29 November 2018

15 March 2019

Quick facts

Lead sponsor	Charite University, Berlin, Germany
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	84
Start date	21 August 2018
Primary completion	29 November 2018
Estimated completion	15 March 2019
Sites	1 location across Germany

Drugs / interventions tested

Angio-PCI
OCT-PCI
ACR-PCI

Conditions studied

Ischaemic Heart Disease — all drugs for Ischaemic Heart Disease →

Sponsor

Charite University, Berlin, Germany

Who can join

Adults 18 to 85, any sex, with Ischaemic Heart Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Intracoronary optical coherence tomography (OCT) imaging allows for high-resolution characterization of coronary lesions. Difficulties in matching cross-sectional OCT-images with angiographic lesion localization, however, may limit its clinical utilization. The investigators sought to prospectively assess the impact of a novel system of real-time OCT-coregistration with angiography (ACR) compared to OCT alone and to the clinical standard proceeding (angiographic guided-PCI) all used for coronary lesion evaluation before percutaneous coronary interventions (PCI). The investigators hypothesize that the use of ACR will lead to less incidence of insufficient covered coronary lesions (geographical mismatch) and/or a less rate of edge dissections after PCI (combined primary study endpoint)

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Impact of real-time angiographic co-registered optical coherence tomography on percutaneous coronary intervention: the OPTICO-integration II trial.
Schneider VS, Böhm F, Blum K, Riedel M, et al · · 2021 · cited 12× · PMID 32889633 · DOI 10.1007/s00392-020-01739-1

Verify or expand the search:

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Other Charite University, Berlin, Germany trials

Trials by the same sponsor.

NCT07486167 — Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congeni · Phase 1, PHASE2 · not yet recruiting
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NCT07503054 — Ovarian Cancer Screening and AI · NA · not yet recruiting
NCT07529197 — Observational Study on Immunoadsorption (IA) in Patients With Autoantibody-Positive Post-Infectious ME/CFS · recruiting
NCT07388693 — Feasibility of Integrating Olfactory Stimuli Into Virtual Reality Cue Exposure for Patients With Alcohol Dependence · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03646097 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Charite University, Berlin, Germany
Last refreshed: 23 April 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03646097.

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