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NCT04014140: iCABG
iFR Guided Coronary Artery Bypass Grafting Surgery
trial testing Coronary artery bypass grafting surgery (CABG) in Ischaemic Heart Disease in 100 participants. Currently enrolling.
31 August 2025
Quick facts
| Lead sponsor | Prakash Punjabi |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 25 April 2022 |
| Primary completion | 31 August 2025 |
| Estimated completion | 31 August 2026 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Coronary artery bypass grafting surgery (CABG)
Conditions studied
- Ischaemic Heart Disease — all drugs for Ischaemic Heart Disease →
- Coronary Artery Disease — all drugs for Coronary Artery Disease →
- Coronary Stenosis — all drugs for Coronary Stenosis →
Sponsor
Prakash Punjabi
Who can join
Adults 25 to 80, any sex, with Ischaemic Heart Disease or Coronary Artery Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The expected outcome of better and improved patency of bypass grafts and its direct relation to pre-operative iFR measurements of stenosis as compared to direct visual physiology of stenosis in the coronary angiogram. To establish the correlation between the use of intracoronary physiology and improved graft patency at 12 months for patients undergoing CABG surgery. It is a minimum of 28 and a maximum of 100 patients single-centre proof or concept/ observational study/ pilot study.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04014140
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04014140 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Prakash Punjabi
- Last refreshed: 21 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04014140.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing