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NCT03636100
Release of Acetylcholine From the Ganglionated Plexus During the Thaw Phase of Cryoballon Pulmonary Vein Ablation (GP RESPONSE Study)
trial testing Cryoballoon ablation in Atrial Fibrillation in 7 participants. Terminated before completion.
11 October 2019
Quick facts
| Lead sponsor | Saint Luke's Health System |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 7 |
| Start date | 15 August 2018 |
| Primary completion | 11 October 2019 |
| Estimated completion | 11 October 2019 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Cryoballoon ablation
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
Sponsor
Saint Luke's Health System — full company profile →
Who can join
Adults 18 to 80, any sex, with Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Determine whether the presence of acetylcholine in the systemic circulation, correlates with the hypotensive response observed during the thaw phase of cryoballoon ablation.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Neuromodulation for the Treatment of Heart Rhythm Disorders.
Waldron NH, Fudim M, Mathew JP, Piccini JP. · · 2019 · cited 38× · PMID 31468010 · DOI 10.1016/j.jacbts.2019.02.009
Verify or expand the search:
- PubMed search for NCT03636100
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Cryoballoon ablation
Trials testing the same drug.
- NCT04269785 — Inflammatory and Endothelial Function Response, and Arrhythmia Recurrence Following Catheter Ablation for Atrial Fibrill · NA · withdrawn
- NCT04342832 — Cryoballoon Ablation Versus Medical Therapy in Patients With Heart Failure and Atrial Fibrillation · NA · terminated
- NCT03564925 — Wide Area Circumferential Ablation With Contact Force Versus Cryoballoon Ablation · NA · unknown
- NCT03700307 — Effects of Different Surgical Methods for Persistent Atrial Fibrillation Combined With the Application of Statin Drugs o · NA · completed
- NCT03573869 — Atrial FIbrillation Treatment With Cryoballoon in Heart failurE (AFICHE) · NA · unknown
Other recruiting trials for Atrial Fibrillation
Currently open trials in the same condition.
- NCT07429214 — A Study of VARIPULSE Catheter and TRUPULSE Generator With VARIPULSE Pro Software in Participants With PAF or PsAF · NA · recruiting
- NCT07271238 — Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures · NA · recruiting
- NCT07388108 — Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery. · recruiting
- NCT07428967 — AV Node Ablation and CONDUCTion System Pacing for Atrial Fibrillation With Preserved Left Ventricular Function · NA · recruiting
- NCT06650995 — AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure · NA · recruiting
Other Saint Luke's Health System trials
Trials by the same sponsor.
- NCT06969365 — Weighted Blankets for IUD Insertion · Phase 1 · enrolling by invitation
- NCT05900362 — Feasibility and Success Trial of Remote Patient Monitoring in Heart Failure · NA · not yet recruiting
- NCT05093764 — Quantification of Debris Captured Using TCEP During VIV TAVR With BVF · NA · recruiting
- NCT05089864 — STAR and Deferred Stenting Study · NA · completed
- NCT03664466 — Astaxanthin Effects on Osteoarthritis Associated Pain and Inflammatory Indicators · NA · withdrawn
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03636100 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Saint Luke's Health System
- Last refreshed: 19 October 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03636100.
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