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NCT03635619

The Application of 3T MRI in Esophageal Cancer

Status unknown Last updated 1 April 2020
What this trial tests

trial testing No intervention in Esophageal Cancer TNM Staging in 400 participants. Status unknown.

Timeline
2 September 2018
Primary endpoint
30 December 2023
30 December 2023

Quick facts

Lead sponsorHenan Cancer Hospital
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment400
Start date2 September 2018
Primary completion30 December 2023
Estimated completion30 December 2023
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Henan Cancer Hospital

Who can join

Adults 18 to 75, any sex, with Esophageal Cancer TNM Staging or Magnetic Resonance Imaging. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It is very significant that assessing TN staging in esophageal cancer patients before surgery, furthermore, determining the optimize surgical strategy, predict the the efficacy of radiotherapy for patients who were not chosen to be surgeried, and define the range of lymph node for radiotherapy. It has been reported that the application of MRI in metastasis of lymph node of other cancer, but not in metastasis lymph node with esophageal cancer. Only a few studies focused on T staging using conventional MRI in esophageal cancer, however, relatively new sequences in the chest deserve widely used. To develop a pre-treatment evaluation methods for TN staging in patient with esophageal cancer by utilization of the new imaging methods (T2-TSE-BLADE, T2 maps, StarVIBE). By analysising the relationship between TN staging and imaging features to find the imaging characteristics for TN staging, and to find the indicators of magnetic resonance imaging new technology and reference values for facilitate pre-treatment diagnosis of lymphnode metastasis, optimize surgical strategy, predict the the efficacy of adjunctive therapy, and OS and define the range of lymph node for radiotherapy, as making personal treatment planning for esophageal cancer.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Automated segmentation of esophageal squamous cell carcinoma in contrast-enhanced free-breathing 3D-GRE: a comparative study of UNet, nnUNet, and UMamba for tumor delineation.
    Han B, Chu F, Shi L, Hu C, et al · · 2025 · PMID 41219837 · DOI 10.1186/s12880-025-02011-6
  2. ECR 2025 Book of Abstracts.
    · 2025 · PMID 40676413 · DOI 10.1186/s13244-025-02003-8

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Other trials of No intervention

Trials testing the same drug.

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Trials by the same sponsor.

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