NCT03634943: ENPIC

Evaluation of Nutritional Practices in the Critical Care

Completed Last updated 23 March 2022

What this trial tests

trial testing Patients with Nutritional Support in Nutritional Support in 642 participants. Completed in 22 March 2022.

Timeline

23 April 2018

Primary endpoint
15 September 2018

22 March 2022

Quick facts

Lead sponsor	Hospital Universitari de Bellvitge
Status	Completed
Study type	OBSERVATIONAL
Enrollment	642
Start date	23 April 2018
Primary completion	15 September 2018
Estimated completion	22 March 2022
Sites	43 locations across Spain

Drugs / interventions tested

• Patients with Nutritional Support

Conditions studied

• Nutritional Support — all drugs for Nutritional Support →
• Intensive Care Unit — all drugs for Intensive Care Unit →
• Critical Illness — all drugs for Critical Illness →

Sponsor

Hospital Universitari de Bellvitge

Who can join

18 and older, any sex, with Nutritional Support or Intensive Care Unit. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: The adequacy of the artificial Nutritional Support (NS) in the critical care patient has implications in morbidity and prognosis. Clinical practice guidelines (CPG) are an important tool for healthcare professionals in their daily practice and a method of consultation for the correct treatment of patients. Also, the evidence remains low and there are important controversies regarding the NS in the critical care patient.

Hypothesis: The NS generates great controversy in the professionals involved in the care of critical care patients due to the contradictory results in literature. Despite this, the CPG should serve to standardize the treatment of patients and provide a better adherence to current knowledge in this setting. The importance of NS is underestimated and there is a need to perform proper evaluation of the impact of nutrition.

Objectives: To evaluate and analyze NS practices in critically ill patients in different ICUs and assess the adherence to CPGs. To evaluate the relationship of nutrition and outcomes in the ICU.

Methodology: Prospective multicenter observational study. Collection of variables from different participating ICUs and the characteristics of the NS of the different admitted patients. Monitoring of nutritional practices and complications. Evaluation of outcomes (e.g. mortality, ICU complications, etc.) with NS.

Expected results: Better understanding of the NS and its impact on morbidity and mortality; development of strategies to reduce low adherence to CPGs, improving the quality of care associated with this field in critical care patients; obtain clinical information that will serve as a basis for conducting intervention studies.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. The Effect of Enteral Immunonutrition in the Intensive Care Unit: Does It Impact on Outcomes?
   Lopez-Delgado JC, Grau-Carmona T, Trujillano-Cabello J, García-Fuentes C, et al · · 2022 · cited 8× · PMID 35565870 · DOI 10.3390/nu14091904
2. Factors associated with the need of parenteral nutrition in critically ill patients after the initiation of enteral nutrition therapy.
   Lopez-Delgado JC, Servia-Goixart L, Grau-Carmona T, Bordeje-Laguna L, et al · · 2023 · cited 5× · PMID 37693244 · DOI 10.3389/fnut.2023.1250305
3. Factors associated with the need of Parenteral Nutrition in Critically Ill patients with Enteral Nutrition Therapy
   Lopez-Delgado JC, Grau-Carmona T, Bordeje-Laguna ML, Portugal-Rodriguez E, et al · · 2022 · DOI 10.21203/rs.3.rs-1979076/v1