NCT03632876 is a NA clinical trial of retinyl palmitate in Sickle Cell Anemia in Children, sponsored by Children's Hospital of Philadelphia.

Who is sponsoring NCT03632876?

NCT03632876 is sponsored by Children's Hospital of Philadelphia.

What drugs are being tested in NCT03632876?

Interventions in NCT03632876: retinyl palmitate.

What condition does NCT03632876 study?

NCT03632876 studies Sickle Cell Anemia in Children, Vitamin A Deficiency in Children.

Is NCT03632876 still recruiting?

NCT03632876 is currently completed. Last updated 16 August 2018.

Last reviewed 2018-08-16 · How we verify

NCT03632876

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Nutritional Outcomes After Vitamin A Supplementation in Subjects With SCD

Completed NA Last updated 16 August 2018

What this trial tests

NA trial testing retinyl palmitate in Sickle Cell Anemia in Children in 42 participants. Completed in 30 September 2016.

Timeline

2 October 2015

Primary endpoint
30 September 2016

30 September 2016

Quick facts

Lead sponsor	Children's Hospital of Philadelphia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	42
Start date	2 October 2015
Primary completion	30 September 2016
Estimated completion	30 September 2016
Sites	1 location across United States

Drugs / interventions tested

retinyl palmitate — full drug profile →

Conditions studied

Sickle Cell Anemia in Children — all drugs for Sickle Cell Anemia in Children →
Vitamin A Deficiency in Children — all drugs for Vitamin A Deficiency in Children →

Sponsor

Children's Hospital of Philadelphia

Who can join

9 and older, any sex, with Sickle Cell Anemia in Children or Vitamin A Deficiency in Children. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study establishes the safety and efficacy of vit A supplementation doses (3000 and 6000 IU/d) over 8 weeks in children with SCD-SS, ages 9 and older and test the impact of vit A supplementation on key functional and clinical outcomes. Additionally, vitamin A status is assessed in healthy children ages 9 and older to compare to subjects with SCD-SS.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Use of Compartmental Modeling and Retinol Isotope Dilution to Determine Vitamin A Stores in Young People with Sickle Cell Disease Before and After Vitamin A Supplementation.
Ford JL, Green MH, Brownell JN, Green JB, et al · · 2023 · cited 3× · PMID 37468045 · DOI 10.1016/j.tjnut.2023.07.004

Verify or expand the search:

Other trials of retinyl palmitate

Trials testing the same drug.

NCT04080869 — Retinyl Palmitate-loaded Ethosomes in Acne Vulgaris · Phase 2 · completed

Other recruiting trials for Sickle Cell Anemia in Children

Currently open trials in the same condition.

NCT05285917 — Promoting Utilization and Safety of Hydroxyurea Using Precision in Africa · Phase 3 · recruiting
NCT06387758 — Low Systemic/High Local Exercise Load in Peds SCD · NA · recruiting

Other Children's Hospital of Philadelphia trials

Trials by the same sponsor.

NCT07023380 — EoE Food Test Pilot Study · NA · not yet recruiting
NCT06693752 — CEUS Evaluation of Hydrocephalus in Neonates and Infants · Phase 2 · recruiting
NCT07425691 — SPACE for Youth With Chronic Pain · recruiting
NCT07444528 — Upper Airway Ultrasound to Predict Difficult Laryngoscopy in Neonates and Infants · enrolling by invitation
NCT07321327 — Implementation Strategies for Caregiver and Teacher Use of Behavioral Interventions: Aim 2 · NA · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03632876 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Children's Hospital of Philadelphia
Last refreshed: 16 August 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03632876.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing