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NCT07444528
Upper Airway Ultrasound to Predict Difficult Laryngoscopy in Neonates and Infants
trial testing Upper airway ultrasound in Neonates in 180 participants. Enrolling by invitation.
31 December 2027
Quick facts
| Lead sponsor | Children's Hospital of Philadelphia |
|---|---|
| Status | ENROLLING BY INVITATION |
| Study type | OBSERVATIONAL |
| Enrollment | 180 |
| Start date | 2 March 2026 |
| Primary completion | 31 December 2027 |
| Estimated completion | 31 December 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Upper airway ultrasound
Conditions studied
- Neonates — all drugs for Neonates →
- Infants Aged 0 Days to 12 Months Scheduled for Elective Surgery — all drugs for Infants Aged 0 Days to 12 Months Scheduled for Elective Surgery →
Sponsor
Children's Hospital of Philadelphia
Who can join
Under 365 Days, any sex, with Neonates or Infants Aged 0 Days to 12 Months Scheduled for Elective Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Upper airway ultrasound (UA-US) has been utilized in adults to predict difficult laryngoscopy (Cormick-Lehane view 3 or 4) and difficult tracheal intubation (DTI) (≥3 intubation attempts) and with moderate-to-high sensitivity and specificity. This bedside technique is reproducible, easy-to-do without any additional radiation risk, and was added to the most recent American Society of Anesthesiologists (ASA) Practice Guidelines for Difficult Airway Management in Adults. However, UA-US has only been applied to older children ages 5-12 and has not been examined in neonates and infants. Thus, the aim of this observational study using UA-US to predict difficult laryngoscopy and tracheal intubation in neonates and infants presenting for diagnostic, procedural or surgical care under general anesthesia requiring endotracheal intubation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07444528
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07444528 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Children's Hospital of Philadelphia
- Last refreshed: 4 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07444528.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing