NCT03632044 is a Phase 4 clinical trial of Ropivacaine in Mouth Abnormalities, sponsored by University of Florida.

Who is sponsoring NCT03632044?

NCT03632044 is sponsored by University of Florida.

What drugs are being tested in NCT03632044?

Interventions in NCT03632044: Ropivacaine, Sham Comparator.

What condition does NCT03632044 study?

NCT03632044 studies Mouth Abnormalities, Cleft Palate, Birth Defect.

Is NCT03632044 still recruiting?

NCT03632044 is currently active, enrolled. Last updated 20 January 2026.

Last reviewed 2026-01-20 · How we verify

NCT03632044

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of Trigeminal Nerve Blockade

Active, enrolled Phase 4 Last updated 20 January 2026

What this trial tests

Phase 4 trial testing Ropivacaine in Mouth Abnormalities in 40 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

20 November 2018

Primary endpoint
31 May 2026

30 October 2027

Quick facts

Lead sponsor	University of Florida
Phase	Phase 4
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	40
Start date	20 November 2018
Primary completion	31 May 2026
Estimated completion	30 October 2027
Sites	1 location across United States

Drugs / interventions tested

Ropivacaine (ROPIVACAINE) — full drug profile →
Sham Comparator

Conditions studied

Mouth Abnormalities — all drugs for Mouth Abnormalities →
Cleft Palate — all drugs for Cleft Palate →
Birth Defect — all drugs for Birth Defect →

Sponsor

University of Florida

Who can join

Adults 3 Months to 5, any sex, with Mouth Abnormalities or Cleft Palate. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cleft palate repair requires high doses of opioids for pain control postop. An alternative approach is placement of nerve blocks in the pterygopalatine fossa bilaterally, blocking the maxillary nerve \& covering the entire midface. Application of bilateral suprazygomatic maxillary nerve blockade of the infraorbital nerve may provide effective analgesia for cleft lip repair, improving time to oral intake, pain control and time to hospital discharge.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Ropivacaine

Trials testing the same drug.

NCT07116343 — Intrapleural Ropivacaine Infusion in Cardiac Surgery · Phase 4 · recruiting
NCT07209345 — Pre-emptive Scalp Infiltration With Low-dose Flurbiprofen and Ropivacaine for Postoperative Analgesia After Craniotomy · NA · recruiting
NCT05642026 — INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures · Phase 4 · recruiting
NCT07013526 — Dexmedetomidine as Adjuvant for Suprazygomatic Maxillary Nerve Block in Children's Adenotonsillectomy · NA · not yet recruiting
NCT06925789 — Influence of Standardized Perioperative Anesthetic, Analgesic Care on Outcome of Patients Undergoing Hip Fracture Surger · Phase 1 · withdrawn

Other University of Florida trials

Trials by the same sponsor.

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NCT07507214 — Optimized, Neuroplasticity-Enhanced-Depression (ONE-D) Transcranial Magnetic Stimulation (TMS) Treatment for Female Athl · Phase 2, PHASE3 · not yet recruiting
NCT07492316 — RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB) · Phase 1 · not yet recruiting
NCT06670794 — Using Ecological Momentary Data to Inform a Web Intervention for Romantic Partners Concerned About Their Loved Ones' Dri · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03632044 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Florida
Last refreshed: 20 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03632044.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing