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NCT03612609: DENGSPERM
Pilot Study to Detect DENGUE Virus in Sperm
NA trial testing blood, urine and semen sample in Dengue in 10 participants. Completed in 7 August 2019.
7 August 2019
Quick facts
| Lead sponsor | University Hospital, Toulouse |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 10 |
| Start date | 6 February 2019 |
| Primary completion | 7 August 2019 |
| Estimated completion | 7 August 2019 |
| Sites | 1 location across Reunion |
Drugs / interventions tested
- blood, urine and semen sample — full drug profile →
Conditions studied
- Dengue — all drugs for Dengue →
Sponsor
University Hospital, Toulouse
Who can join
Adults 18 to 45, male only, with Dengue. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to seek the presence of dengue virus in semen, to determine its localization and to assess the efficiency of spermatozoa processing methods to obtain virus free spermatozoa. This is a prospective study involving 15 patients, with acute dengue virus infection and a positive RNA detection in blood or/and urines. These results are important to understand the physiopathology of dengue virus infection and will help to counsel the infected patient in epidemic zona or returning from epidemic country. Moreover, they will help to define the management and viral safety procedures during Medically assisted Procreation in the context of dengue virus epidemic
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
The Cellular Impact of the ZIKA Virus on Male Reproductive Tract Immunology and Physiology.
Almeida RDN, Braz-de-Melo HA, Santos IO, Corrêa R, et al · · 2020 · cited 23× · PMID 32325652 · DOI 10.3390/cells9041006 -
Effects of Acute Dengue Infection on Sperm and Virus Clearance in Body Fluids of Men.
Mons J, Mahé-Poiron D, Mansuy JM, Lheureux H, et al · · 2022 · cited 13× · PMID 35608553 · DOI 10.3201/eid2806.212317
Verify or expand the search:
- PubMed search for NCT03612609
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Dengue
Currently open trials in the same condition.
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- NCT07007585 — Risk Factors for Hospitalization and Transfusion Criteria in Patients With Dengue Virus Infection · recruiting
- NCT06894901 — Impact of IIT-SIT on Dengue Clusters · NA · recruiting
- NCT07158190 — Evaluation of T-cell Responses After Vaccination With the Attenuated Tetravalent Dengue Vaccine (Takeda). · active not recruiting
Other University Hospital, Toulouse trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03612609 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Toulouse
- Last refreshed: 5 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03612609.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing