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NCT03610763
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
NA trial testing Transcranial Direct Current Stimulation in Hand Transplantation in 180 participants. Currently enrolling.
1 June 2025
Quick facts
| Lead sponsor | University of Missouri-Columbia |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 180 |
| Start date | 15 August 2018 |
| Primary completion | 1 June 2025 |
| Estimated completion | 1 June 2025 |
| Sites | 3 locations across United States |
Drugs / interventions tested
- Transcranial Direct Current Stimulation
- Modified Constraint Induced Movement Therapy
Conditions studied
- Hand Transplantation — all drugs for Hand Transplantation →
- Peripheral Nerve Injuries — all drugs for Peripheral Nerve Injuries →
- Neurologic Rehabilitation — all drugs for Neurologic Rehabilitation →
Sponsor
University of Missouri-Columbia
Who can join
18 and older, any sex, with Hand Transplantation or Peripheral Nerve Injuries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study adopts a strategy that has arisen from basic neuroscience research on facilitating adaptive brain plasticity and applies this to rehabilitation to improve functional recovery in peripheral nervous system injuries (including hand transplantation, hand replantation, and surgically repaired upper extremity nerve injuries). The technique involves combining behavioral training with transcranial direct current stimulation (tDCS)-a non-invasive form of brain stimulation capable of facilitating adaptive changes in brain organization.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03610763
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transcranial Direct Current Stimulation
Trials testing the same drug.
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- NCT07395531 — Effect of Repetitive Bihemispheric Anodal Transcranial Direct Current Stimulation on Motor Function of Patients With Par · Phase 3 · not yet recruiting
- NCT07212634 — Cerebellar Transcranial Direct Current Stimulation for Dysphagia After Supratentorial Stroke · NA · not yet recruiting
- NCT07319143 — The Effect of Transcranial Direct Current Stimulation (tDCS) in Improving Emotion Health · NA · recruiting
- NCT06039605 — Priming Expectations and Motor Learning With tDCS · NA · completed
Other University of Missouri-Columbia trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03610763 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Missouri-Columbia
- Last refreshed: 12 June 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03610763.
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