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NCT07395531

Effect of Repetitive Bihemispheric Anodal Transcranial Direct Current Stimulation on Motor Function of Patients With Parkinson's Disease

Not yet recruiting Phase 3 Last updated 9 February 2026
What this trial tests

Phase 3 trial testing Transcranial Direct Current Stimulation in PARKINSON DISEASE (Disorder) in 30 participants. Not yet recruiting.

Timeline
1 February 2026
Primary endpoint
30 June 2026
31 July 2026

Quick facts

Lead sponsorDr. Ram Manohar Lohia Hospital
PhasePhase 3
StatusNot yet recruiting
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposehealth services research
Enrollment30
Start date1 February 2026
Primary completion30 June 2026
Estimated completion31 July 2026
Sites1 location across India

Drugs / interventions tested

Conditions studied

Sponsor

Dr. Ram Manohar Lohia Hospital

Who can join

Eligibility, any sex, with PARKINSON DISEASE (Disorder) or Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Dopaminergic medications and Deep Brain Stimulation (DBS) are the current standards interventions for Parkinson's Disease. Pharmacotherapy with dopaminergic drugs leads to partial improvement in motor functions of patients. Invasive therapies like DBS have as yet limited availability and accessibility, with risk of adverse events as well. Non invasive therapies like Transcranial Direct Current Stimulation (tDCS) are currently increasingly being probed for their therapeutic value, in view of their safety, portability and convenience of administration. Improvement in motor function immediately after a single session of tDCS has been observed. The effect of single simulation is not sustained beyond a few days. Only few studies with varied sites of stimulation have evaluated the effect of repetitive tDCS on motor function improvement in patients with Parkinson's Disease, with conflicting results. There is an unmet need to probe the utility of repetitive tDCS on motor function of patients with Parkinson's Disease. We aim to probe the effect of repetitive tDCS of dorsolateral prefrontal cortex and M1 cortex on motor function in patients with Parkinson's Disease (Hoehn and Yahr stage 2 to 4).

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other trials of Transcranial Direct Current Stimulation

Trials testing the same drug.

Other recruiting trials for PARKINSON DISEASE (Disorder)

Currently open trials in the same condition.

Other Dr. Ram Manohar Lohia Hospital trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing