NCT03606330 (VIP) is a clinical trial of Cardiac imaging tests in Coronary Stenosis, sponsored by Cardio Med Medical Center.

Who is sponsoring NCT03606330?

NCT03606330 is sponsored by Cardio Med Medical Center.

What drugs are being tested in NCT03606330?

Interventions in NCT03606330: Cardiac imaging tests, Venous blood sample collection.

What condition does NCT03606330 study?

NCT03606330 studies Coronary Stenosis, Acute Coronary Syndrome, Acute Myocardial Infarction, Atheromatous Plaques, Atheroscleroses, Coronary, Non-ST Elevation Myocardial Infarction (nSTEMI).

Is NCT03606330 still recruiting?

NCT03606330 is currently completed. Last updated 2 August 2022.

Last reviewed 2022-08-02 · How we verify

NCT03606330: VIP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Systemic, Pancoronary and Local Coronary Vulnerability

Completed Last updated 2 August 2022

What this trial tests

trial testing Cardiac imaging tests in Coronary Stenosis in 100 participants. Completed in 1 March 2022.

Timeline

22 October 2018

Primary endpoint
22 October 2019

1 March 2022

Quick facts

Lead sponsor	Cardio Med Medical Center
Status	Completed
Study type	OBSERVATIONAL
Enrollment	100
Start date	22 October 2018
Primary completion	22 October 2019
Estimated completion	1 March 2022
Sites	1 location across Romania

Drugs / interventions tested

Cardiac imaging tests
Venous blood sample collection

Conditions studied

Coronary Stenosis — all drugs for Coronary Stenosis →
Acute Coronary Syndrome — all drugs for Acute Coronary Syndrome →
Acute Myocardial Infarction — all drugs for Acute Myocardial Infarction →
Atheromatous Plaques — all drugs for Atheromatous Plaques →

Sponsor

Cardio Med Medical Center

Who can join

18 and older, any sex, with Coronary Stenosis or Acute Coronary Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

• The aim of the VIP study is to investigate the impact of vulnerability markers (inflammatory serum biomarkers for systemic vulnerability, coronary shear stress and vulnerability mapping for pancoronary vulnerability, and imaging-based plaque features for systemic vulnerability) on the rate of major adverse cardiovascular events caused by progression of the non-culprit lesion in patients with acute ST or non-ST segment elevation myocardial infarction who undergo revascularization of the culprit lesion during the acute event. Furthermore, the study will evaluate the rate of progression of non-culprit lesions towards a higher degree of vulnerability, based on coronary computed tomography angiographic assessment at 1 year after enrollment.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Systemic Vulnerability, as Expressed by I-CAM and MMP-9 at Presentation, Predicts One Year Outcomes in Patients with Acute Myocardial Infarction-Insights from the VIP Clinical Study.
Opincariu D, Rodean I, Rat N, Hodas R, et al · · 2021 · cited 5× · PMID 34362217 · DOI 10.3390/jcm10153435

Verify or expand the search:

Other trials of Cardiac imaging tests

Trials testing the same drug.

NCT03757741 — Inflammation, Fibrosis and Risk of Recurrence After Atrial Fibrillation Ablation · completed

Other recruiting trials for Coronary Stenosis

Currently open trials in the same condition.

NCT06535568 — Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO · NA · recruiting
NCT06542393 — PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG) · Phase 2 · recruiting
NCT05709652 — Impact of Fast-rotation Coronary CT in Patients Undergoing Aortic Stenosis Workup · NA · recruiting
NCT06376630 — Study of Microvascular Dysfunction, CFR and Cardioprotective Effect of Early Administration of Esmolol in MI · NA · recruiting
NCT04014140 — iFR Guided Coronary Artery Bypass Grafting Surgery · recruiting

Other Cardio Med Medical Center trials

Trials by the same sponsor.

NCT04680689 — Assessment of Lesion-Associated Myocardial Ischemia Based on Fusion Coronary CT Imaging · completed
NCT04397198 — The Assessment Of Myocardial Viability Based On CTA/MRI Hybrid Models · completed
NCT04161378 — Impact of Cardiac Rehabilitation Programs on Left Ventricular Remodeling After Acute Myocardial Infarction - the REHAB T · completed
NCT03830944 — Inflammation-mediated Coronary Plaque Vulnerability, Myocardial Viability and Ventricular Remodeling · completed
NCT03757741 — Inflammation, Fibrosis and Risk of Recurrence After Atrial Fibrillation Ablation · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03606330 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cardio Med Medical Center
Last refreshed: 2 August 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03606330.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing