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NCT03604965
GP Induction Chemotherapy us TPF Adjuvant Chemotherapy Combined With DDP Concurrent Chemoradiotherapy in the Treatment of Locally Advanced NPC
Phase 3 trial testing GP+CCRT in Locally Advanced Nasopharyngeal Carcinoma in 204 participants. Status unknown.
21 July 2020
Quick facts
| Lead sponsor | Guiyang Medical University |
|---|---|
| Phase | Phase 3 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 204 |
| Start date | 21 July 2018 |
| Primary completion | 21 July 2020 |
| Estimated completion | 21 July 2020 |
| Sites | 1 location across China |
Drugs / interventions tested
Conditions studied
- Locally Advanced Nasopharyngeal Carcinoma — all drugs for Locally Advanced Nasopharyngeal Carcinoma →
Sponsor
Guiyang Medical University
Who can join
Adults 18 to 69, any sex, with Locally Advanced Nasopharyngeal Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Through randomized controlled phase III multicenter clinical trials, GP induction chemotherapy vs TPF regimen adjuvant chemotherapy combined with DDP concurrent chemoradiotherapy for the treatment of locally advanced nasopharyngeal carcinoma: the efficacy, toxicity and quality of life, and further improvement Survival rate and improve the quality of life.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The efficacy and safety of induction chemotherapy combined with concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in nasopharyngeal carcinoma patients: a systematic review and meta-analysis.
Wang BC, Xiao BY, Lin GH, Wang C, et al · · 2020 · cited 12× · PMID 32375701 · DOI 10.1186/s12885-020-06912-3
Verify or expand the search:
- PubMed search for NCT03604965
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of GP+CCRT
Trials testing the same drug.
- NCT06605131 — GP Combined with Toripalimab Versus GP Induction Chemotherapy for Advanced Childhood Nasopharyngeal Carcinoma · Phase 2 · not yet recruiting
Other recruiting trials for Locally Advanced Nasopharyngeal Carcinoma
Currently open trials in the same condition.
- NCT07085234 — Iparomlimab/Tuvorlimab (QL1706) and Modified TPF Regimen for Induction Therapy in LANPC · Phase 2 · recruiting
- NCT05892354 — Effect of Immunonutrients on Oral Mucositis in Nasopharyngeal Carcinoma Patients After Chemoradiotherapy · NA · recruiting
- NCT05397769 — Envafolimab Plus Chemoradiotherapy for Locally Advanced NPC, a Prospective, Single Armed Phase II Trial. · Phase 2 · recruiting
- NCT05062005 — ICCRT vs. CRT for Locally Advanced Nasopharyngeal Carcinoma · Phase 3 · recruiting
Other Guiyang Medical University trials
Trials by the same sponsor.
- NCT03723343 — GP-induced Chemotherapy Combined With IMRT and TPF-induced Chemotherapy Combined With IMRT in the Treatment of Distant M · unknown
- NCT03557112 — By Comparing TPF Induction Chemotherapy Combined With Nimotuzumab Concurrent Radiotherapy and Cisplatin Concurrent Radio · Phase 2 · unknown
- NCT03574324 — TPF Induction Chemotherapy vs PF Adjuvant Chemotherapy Combined With Concurrent Chemoradiotherapy in the Treatment of Lo · Phase 3 · unknown
- NCT03196869 — the Study of Effect of Chronomodulated Chemotherapy on the Dendritic Cells Subsets in the Treatment of Advanced Nasophar · Phase 2 · unknown
- NCT03117257 — Docetaxel and Loplatin Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced SCCHN · Phase 2 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03604965 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Guiyang Medical University
- Last refreshed: 30 July 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03604965.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing