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NCT05892354
Effect of Immunonutrients on Oral Mucositis in Nasopharyngeal Carcinoma Patients After Chemoradiotherapy
NA trial testing Enteral immunonutrition in Locally Advanced Nasopharyngeal Carcinoma in 190 participants. Currently enrolling.
30 April 2025
Quick facts
| Lead sponsor | First Affiliated Hospital of Guangxi Medical University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 190 |
| Start date | 12 June 2023 |
| Primary completion | 30 April 2025 |
| Estimated completion | 1 April 2027 |
| Sites | 20 locations across China |
Drugs / interventions tested
- Enteral immunonutrition
- Standard enteral nutrition
Conditions studied
- Locally Advanced Nasopharyngeal Carcinoma — all drugs for Locally Advanced Nasopharyngeal Carcinoma →
Sponsor
First Affiliated Hospital of Guangxi Medical University
Who can join
Adults 18 to 70, any sex, with Locally Advanced Nasopharyngeal Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study was to investigate the role of immunonutrion compared with standard nutrition in reducing oral mucositis in patients with locally advanced nasopharyngeal carcinoma.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Nutritional status, immunonutrition, and gut microbiome: a coming of age for immunotherapy?
Mattavelli E, Agustoni F, Tartara A, De Simeis F, et al · · 2025 · cited 3× · PMID 40927712 · DOI 10.3389/fimmu.2025.1612567
Verify or expand the search:
- PubMed search for NCT05892354
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Locally Advanced Nasopharyngeal Carcinoma
Currently open trials in the same condition.
- NCT07085234 — Iparomlimab/Tuvorlimab (QL1706) and Modified TPF Regimen for Induction Therapy in LANPC · Phase 2 · recruiting
- NCT05397769 — Envafolimab Plus Chemoradiotherapy for Locally Advanced NPC, a Prospective, Single Armed Phase II Trial. · Phase 2 · recruiting
- NCT05062005 — ICCRT vs. CRT for Locally Advanced Nasopharyngeal Carcinoma · Phase 3 · recruiting
Other First Affiliated Hospital of Guangxi Medical University trials
Trials by the same sponsor.
- NCT07459296 — Becotatug Vedotin Plus Sintilimab in Locoregionally Advanced NPC · Phase 3 · recruiting
- NCT07342322 — A Prospective, Multicenter, Open-label, Single-arm Phase II Clinical Study Evaluating the Efficacy and Safety of Spatial · Phase 2 · not yet recruiting
- NCT07338357 — Clinical Study of CLL-1 CAR-T in the Treatment of Children With R/R AML · EARLY_PHASE1 · not yet recruiting
- NCT07132008 — Neoadjuvant CAPOX Plus Tislelizumab vs CAPOX in MSS High-Risk Locally Advanced Colon Cancer · Phase 3 · not yet recruiting
- NCT07074444 — Treatment of Clonorchiasis in Guangxi With Albendazole, Tribendimidine, and Praziquantel · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05892354 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by First Affiliated Hospital of Guangxi Medical University
- Last refreshed: 7 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05892354.
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