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NCT03591250: OBSERVE
Healthcare Renunciation in Respiratory Chronic Disease and Treatment Compliance (OBSERVE)
trial in Obstructive Sleep Apnea in 1,083 participants. Completed in 29 August 2022.
29 August 2022
Quick facts
| Lead sponsor | University Hospital, Grenoble |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1,083 |
| Start date | 7 December 2018 |
| Primary completion | 29 August 2022 |
| Estimated completion | 29 August 2022 |
| Sites | 3 locations across France |
Conditions studied
- Obstructive Sleep Apnea — all drugs for Obstructive Sleep Apnea →
- Respiratory Failure — all drugs for Respiratory Failure →
Sponsor
University Hospital, Grenoble
Who can join
18 and older, any sex, with Obstructive Sleep Apnea or Respiratory Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Health care renunciation is a factor that can alter patients' health status and increase the costs of its support. To date, there is no national data on the renunciation of care. This study will initially characterize the different forms of health care renunciation in patients with chronic respiratory diseases, treated with continuous positive airway pressure (CPAP) or non-invasive ventilation (NIV) , and analyze it impact on treatment compliance and health processes. The follow-up of these patients during 5 years will define renunciation trajectories (transition from the state of "renouncing" to "non-renouncing" and vice versa) and their impact on treatment compliance. The investigators hypothesize that a patient becoming renounced on a given treatment also decreases his treatment compliance (CPAP or NIV ). The impact of the renunciation trajectory on the patient's follow-up in terms of hospitalizations and deaths will also be studied.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Impact of Healthcare Non-Take-Up on Adherence to Long-Term Positive Airway Pressure Therapy.
Daabek N, Tamisier R, Foote A, Revil H, et al · · 2021 · cited 3× · PMID 34485235 · DOI 10.3389/fpubh.2021.713313
Verify or expand the search:
- PubMed search for NCT03591250
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University Hospital, Grenoble trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03591250 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Grenoble
- Last refreshed: 3 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03591250.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing