NCT03589560 is a NA clinical trial of Biodentine in Pulp Necrosis, sponsored by Cairo University.

Who is sponsoring NCT03589560?

NCT03589560 is sponsored by Cairo University.

What drugs are being tested in NCT03589560?

Interventions in NCT03589560: Biodentine, Mineral Trioxide Aggregate.

What condition does NCT03589560 study?

NCT03589560 studies Pulp Necrosis.

Is NCT03589560 still recruiting?

NCT03589560 is currently completed. Last updated 18 July 2018.

Last reviewed 2018-07-18 · How we verify

NCT03589560

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of Biodentine and Mineral Trioxide Aggregate in Revascularization of Non Vital Immature Anterior Teeth

Completed NA Last updated 18 July 2018

What this trial tests

NA trial testing Biodentine in Pulp Necrosis in 26 participants. Completed in 15 January 2018.

Timeline

15 January 2015

Primary endpoint
15 August 2017

15 January 2018

Quick facts

Lead sponsor	Cairo University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	26
Start date	15 January 2015
Primary completion	15 August 2017
Estimated completion	15 January 2018

Drugs / interventions tested

Biodentine — full drug profile →
Mineral Trioxide Aggregate — full drug profile →

Conditions studied

Pulp Necrosis — all drugs for Pulp Necrosis →

Sponsor

Cairo University

Who can join

Adults 8 to 15, any sex, with Pulp Necrosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

the object of this study is to evaluate clinically and radiographically the effect of using Biodentine and Mineral Trioxide Aggregate as coronal plug materials in revascularization of non-vital immature teeth

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Efficacy of White Mineral Trioxide Aggregate in Regenerative Endodontic Procedures and Apexification for Immature Permanent Teeth: A Systematic Review and Meta-Analysis.
Li Z, Xu Y, An S, Liu H, et al · · 2026 · PMID 42160814 · DOI 10.1016/j.identj.2026.109611

Verify or expand the search:

Other trials of Biodentine

Trials testing the same drug.

NCT06683833 — Comparison Between Egyptian MTA, Biodentine Versus Calcium Hydroxide as Indirect Pulp Capping Materials In Permanent Tee · Phase 4 · recruiting
NCT07130214 — The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy · active not recruiting
NCT06695208 — Socket Preservation Using Biodentin Versus Xeno Graft for Single Rooted Teeth · Phase 4 · recruiting
NCT05937100 — New Vital Pulpotomy Medications in Primary Molars · NA · active not recruiting
NCT06020911 — Indirect Pulp Capping Using Biodentine and Theracal Light-cured in Primary Molars · Phase 4 · completed

Other recruiting trials for Pulp Necrosis

Currently open trials in the same condition.

NCT07091981 — Effect of Rotary File Number on MB2 Canal Negotiation and Postoperative Pain · NA · recruiting
NCT07391124 — In Vivo Pulp Thermal Changes During Different Slenderization Techniques · NA · active not recruiting

Other Cairo University trials

Trials by the same sponsor.

NCT04155528 — Effect of Music Therapy on Postoperative Health Outcomes · NA · not yet recruiting
NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03589560 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 18 July 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03589560.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing