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NCT03581006
Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Trial
trial testing Low-Calorie Mediterranean Diet in Lung Injury in 100 participants. Completed in 4 March 2021.
4 March 2021
Quick facts
| Lead sponsor | NYU Langone Health |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 12 November 2018 |
| Primary completion | 4 March 2021 |
| Estimated completion | 4 March 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Low-Calorie Mediterranean Diet
- Technology based monitoring and behavioral participation
- Usual care group — full drug profile →
Conditions studied
- Lung Injury — all drugs for Lung Injury →
- Particulate Matter Inhalation Injury — all drugs for Particulate Matter Inhalation Injury →
Sponsor
NYU Langone Health — full company profile →
Who can join
Adults 21 to 90, male only, with Lung Injury or Particulate Matter Inhalation Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a randomized-controlled unblinded clinical trial to investigate dietary intervention on metabolic biomarker assessment in World Trade Center (WTC) Lung Injury (LI) in firefighters. The purpose of this study is to evaluate biomarkers of metabolic dysregulation that have previously been found to predict WTC-LI in a case cohort study selected from the entire exposed firefighter cohort, and attempt to alter these metabolites using dietary intervention and a technology-supported behavioral modification program. Investigators will measure Pre/Post global metabolic expression in WTC-exposed, symptomatic firefighter serum sampled after 6-month intervention, as well as clinical outcomes of WTC-LI in the study group vs controls.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
282 Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE): a Proof of Concept Randomized Clinical Trial
Kwon S, Lam R, Crowley G, Zeig-Owens R, et al ·
Verify or expand the search:
- PubMed search for NCT03581006
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Lung Injury
Currently open trials in the same condition.
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- NCT06416709 — Stem Cell Treatment for Lung Injury Caused by Major Infectious Diseases · Phase 1, PHASE2 · recruiting
Other NYU Langone Health trials
Trials by the same sponsor.
- NCT07214519 — Permanent Supportive Housing Overdose Prevention-2 Study · NA · not yet recruiting
- NCT05558267 — Potassium Containing Salt-Substitute in Hemodialysis-Dependent End Stage Kidney Disease · NA · not yet recruiting
- NCT06637852 — Sexual and Urinary Function Improvement for Cancer Survivors · NA · not yet recruiting
- NCT06236087 — Overdose Prevention Centers and Behavioral Health · not yet recruiting
- NCT06462027 — Packed Red Blood Cell Transfusion During Cardiac Arrest · Phase 1 · suspended
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03581006 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by NYU Langone Health
- Last refreshed: 3 December 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03581006.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing