NCT03580148 (BMAC) is a Phase 2, PHASE3 clinical trial of Cortisone in Osteo Arthritis Shoulders, sponsored by Women's College Hospital.

Who is sponsoring NCT03580148?

NCT03580148 is sponsored by Women's College Hospital.

What drugs are being tested in NCT03580148?

Interventions in NCT03580148: Cortisone, Bone Marrow Aspirate.

What condition does NCT03580148 study?

NCT03580148 studies Osteo Arthritis Shoulders.

Is NCT03580148 still recruiting?

NCT03580148 is currently completed. Last updated 20 July 2022.

Last reviewed 2022-07-20 · How we verify

NCT03580148: BMAC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

BMA vs Cortisone for Glenohumeral Osteoarthritis

Completed Phase 2, PHASE3 Last updated 20 July 2022

What this trial tests

Phase 2, PHASE3 trial testing Cortisone in Osteo Arthritis Shoulders in 34 participants. Completed in 23 November 2021.

Timeline

8 October 2015

Primary endpoint
30 July 2020

23 November 2021

Quick facts

Lead sponsor	Women's College Hospital
Phase	Phase 2, PHASE3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	34
Start date	8 October 2015
Primary completion	30 July 2020
Estimated completion	23 November 2021
Sites	1 location across Canada

Drugs / interventions tested

Cortisone (CORTISONE) — full drug profile →
Bone Marrow Aspirate

Conditions studied

Osteo Arthritis Shoulders — all drugs for Osteo Arthritis Shoulders →

Sponsor

Women's College Hospital

Who can join

Adults 18 to 65, any sex, with Osteo Arthritis Shoulders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This randomized trial seeks to investigate the difference if any between cortisone injection versus bone marrow aspirate injection in the glenohumeral joint of patients with confirmed osteoarthritis. The investigators hope that results from a prospective randomized controlled pilot study on bone marrow aspirate (BMA) glenohumeral joint (GHJ) injections will provide valuable early information on an alternative treatment for GHJ osteoarthritis (OA). This novel study will also contribute clinical data to the growing pool of research around BMA in the treatment of osteoarthritis. This study has the potential to uncover a new and more effective therapy to add to the arsenal of an orthopaedic surgeon in the management of GHJ OA. This would provide improved care and treatment for those disabled by GHJ OA. Additionally, this knowledge would be applicable to a variety of medical practitioners who treat GHJ OA from the general orthopaedic surgeon to pain subspecialists.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Pharmaceutical therapeutics for articular regeneration and restoration: state-of-the-art technology for screening small molecular drugs.
Chen Y, Sun H, Yao X, Yu Y, et al · · 2021 · cited 9× · PMID 34783870 · DOI 10.1007/s00018-021-03983-8

Verify or expand the search:

Other trials of Cortisone

Trials testing the same drug.

NCT06082271 — Comparative, Randomized Study on the Anti-inflammatory and Regenerative Efficacy of a New Medical Device (DM) Based on H · NA · completed
NCT03082339 — Cortisone and QTc-Interval · completed

Other recruiting trials for Osteo Arthritis Shoulders

Currently open trials in the same condition.

NCT06615739 — Comprehensive SRS Regenerex Tissue Attachment · active not recruiting
NCT05700682 — Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee · recruiting
NCT04238143 — Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis · NA · recruiting
NCT04529798 — Clinical Study Evaluating Outcomes of Reverse Shoulder Arthroplasty With SMR Stemless · recruiting
NCT05603728 — Exactech Shoulder Post Market Clinical Follow-up Study · recruiting

Other Women's College Hospital trials

Trials by the same sponsor.

NCT07262008 — Sustained Mood Improvement With Laughing Gas Exposure · Phase 3 · not yet recruiting
NCT07066631 — The Pregnancy and Postpartum Mental Health Optimization Virtual Intervention Network · NA · recruiting
NCT06852339 — Evaluating the EAPOC-COPD System · NA · not yet recruiting
NCT07027852 — My Lung Health Coach-A Virtual COPD Self-management Support Program Integrated Into the Electronic Patient Record · NA · recruiting
NCT06462391 — Adapting and Piloting Acceptance and Commitment Therapy (ACT) for Severe Premenstrual Mood Symptoms · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03580148 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Women's College Hospital
Last refreshed: 20 July 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03580148.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing