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NCT03572114
Imaging Neuromelanin and Iron in Dystonia/Parkinsonism
trial testing 3Tesla MRI in Sporadic Dystonia in 80 participants. Status unknown.
1 July 2021
Quick facts
| Lead sponsor | University College, London |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 80 |
| Start date | 1 July 2018 |
| Primary completion | 1 July 2021 |
| Estimated completion | 1 July 2021 |
Drugs / interventions tested
- 3Tesla MRI
- Burke-Fahn-Marsden Dystonia Rating scale
- MDS-United Parkinsons Disease Rating Scale, Part III
- Beck Depression Inventory
- MoCA: Montreal Cognitive Assessment:
Conditions studied
- Sporadic Dystonia — all drugs for Sporadic Dystonia →
- Dystonia, Familial — all drugs for Dystonia, Familial →
- Parkinson Disease, Juvenile — all drugs for Parkinson Disease, Juvenile →
- Neurodegeneration With Brain Iron Accumulation 5 — all drugs for Neurodegeneration With Brain Iron Accumulation 5 →
Sponsor
University College, London
Who can join
Adults 18 to 60, any sex, with Sporadic Dystonia or Dystonia, Familial. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To generate pilot data to investigate the potential to use in vivo iron- and neuromelanin-quantification as imaging tools for the diagnostic evaluation of movement disorders with predominant dystonia / parkinsonism. To this end we are planning to compare the MR imaging neuromelanin and iron-pattern and content in midbrain, striatum and further brain structures in clinically similar entities and respective, sex- and age-matched healthy controls.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03572114
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03572114 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University College, London
- Last refreshed: 28 June 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03572114.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing