Last reviewed · How we verify
NCT03569189
Impact of a High Saturated Fat Diet on Fasted Systemic and White Adipose Tissue Inflammatory Responses
NA trial testing High Fat Diet in Inflammation in 15 participants. Completed in 23 November 2018.
23 November 2018
Quick facts
| Lead sponsor | Loughborough University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 15 |
| Start date | 2 July 2018 |
| Primary completion | 23 November 2018 |
| Estimated completion | 23 November 2018 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- High Fat Diet
Conditions studied
- Inflammation — all drugs for Inflammation →
- Obesity — all drugs for Obesity →
- Inflammatory Response — all drugs for Inflammatory Response →
- Cardiovascular Diseases — all drugs for Cardiovascular Diseases →
Sponsor
Loughborough University
Who can join
Adults 18 to 40, any sex, with Inflammation or Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will investigate the effect of a 7-day westernised high-fat (65% of kilocalories), high-calorie (150% of requirements) diet on markers of inflammation in the blood and white adipose tissue. Participants will firstly complete a 3-day weight maintenance phase (Days 1-3) before completing a 7-day high fat diet intervention (Days 4-10). On days 4 and 11 participants will complete a laboratory visit where anthropometric measurements, blood and adipose samples will be collected. The investigators hypothesise that consuming a high-fat, high-calorie diet for 7 days will alter the inflammatory responses in white adipose tissue and will induce metabolic endotoxaemia / systemic inflammation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03569189
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of High Fat Diet
Trials testing the same drug.
- NCT05402085 — N=1 Trials of Individual Variability in Post-prandial Glycemic Responses to Diets of Varying Macronutrient Composition · NA · active not recruiting
- NCT03341052 — Characterization of Bile Acid Pathway in Obesity · NA · completed
Other recruiting trials for Inflammation
Currently open trials in the same condition.
- NCT07341087 — Skin Inflammation in Perimenopause: A Probiotic Intervention Proof of Concept Trial · NA · recruiting
- NCT07479940 — Obesity and Aging: Impacts of Nutritional Counseling and Physical Exercise on Telomeres and Senescence Parameters · NA · active not recruiting
- NCT07269847 — Comparing a Healthy Beef-Centric Diet to a Healthy U.S.-Style Diet on Metabolic Health Outcomes in Pre-Diabetic Adults · NA · recruiting
- NCT07171450 — Cognitive Remediation · NA · recruiting
- NCT07411612 — The Association Between Postoperative Inflammatory and Neurological Serum Biomarker Concentrations and Occurrence of Pos · recruiting
Other Loughborough University trials
Trials by the same sponsor.
- NCT07510113 — Probiotic Study in Alcohol Recovery · NA · active not recruiting
- NCT07504952 — Investigating the Impact of Probiotics on Wellbeing in a Community · NA · completed
- NCT06682897 — Simplified Tai Chi Exercises to Improve Function in People With Chronic Ankle Instability · NA · completed
- NCT06669702 — EXercise Therapy in Axial SpA, Inflammation and Biologic Therapy (ExTASI-B) · NA · recruiting
- NCT06849050 — The Influence of Acute Continuous Exercise and Adiposity on Appetite Hormones and Neural Correlates of Visual Food Cues · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03569189 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Loughborough University
- Last refreshed: 4 January 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03569189.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing