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NCT05402085
N=1 Trials of Individual Variability in Post-prandial Glycemic Responses to Diets of Varying Macronutrient Composition
NA trial testing High Protein Diet in Personalized Nutrition in 120 participants. Participants enrolled and being followed up; not accepting new ones.
11 October 2022
Quick facts
| Lead sponsor | National University of Singapore |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 120 |
| Start date | 3 September 2020 |
| Primary completion | 11 October 2022 |
| Estimated completion | 31 December 2024 |
| Sites | 1 location across Singapore |
Drugs / interventions tested
- High Protein Diet
- High Fat Diet
- High Carbohydrate-Low Glycemic Index Diet
- High Carbohydrate-High Glycemic Index Diet
Conditions studied
- Personalized Nutrition — all drugs for Personalized Nutrition →
Sponsor
National University of Singapore
Who can join
Adults 21 to 60, male only, with Personalized Nutrition. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The key objective of this study is to identify the most suitable diet (i.e. high protein, high fat, low GI, high GI) for an individual. Importantly, we further seek to identify the biological determinants of inter-individual variability and to understand how these determinants affect blood glucose. The deep metabolic phenotyping, multi-omics profiling of each subject and fine-mapping of their glycemic responses to different diets will allow us to obtain preliminary data on the mechanistic basis underlying inter-individual dietary glycemic response. Data from this study will form the basis of large clinical trials, the development of novel foods, and/or novel technologies to alter the gut micro-biome for optimal blood glucose control.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05402085
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of High Protein Diet
Trials testing the same drug.
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- NCT06621940 — Effect of Proteins on Antioxidant Capacity · NA · not yet recruiting
- NCT04014296 — Weight Loss in Adults Over 50 with Obesity · NA · completed
- NCT03832933 — Comparing High and Normal Protein Diets for the Dietary Remission of Type 2 Diabetes · NA · completed
Other recruiting trials for Personalized Nutrition
Currently open trials in the same condition.
- NCT06829095 — Personalized Nutrition Counseling and Nutritional Status of Esophageal Cancer and HNSCC Patients Undergoing CCRT · recruiting
Other National University of Singapore trials
Trials by the same sponsor.
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- NCT07375459 — Community-based Mobile-assisted Brief Intervention for Smoking Cessation · NA · recruiting
- NCT07444073 — Assessing Biological Aging in a Real-World Medical Weight Loss Program Using the LinAge2 Clinical Clock · not yet recruiting
- NCT07282041 — Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis · Phase 2, PHASE3 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05402085 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National University of Singapore
- Last refreshed: 15 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05402085.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing