NCT03560180 (iCral) is a clinical trial of Dutch score in Anastomotic Leak, sponsored by Ospedale C & G Mazzoni.

Who is sponsoring NCT03560180?

NCT03560180 is sponsored by Ospedale C & G Mazzoni.

What drugs are being tested in NCT03560180?

Interventions in NCT03560180: Dutch score, Serum C-reactive Protein, serum Procalcitonin.

What condition does NCT03560180 study?

NCT03560180 studies Anastomotic Leak, Colorectal Surgery.

Is NCT03560180 still recruiting?

NCT03560180 is currently status unknown. Last updated 18 June 2018.

Last reviewed 2018-06-18 · How we verify

NCT03560180: iCral

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Early Diagnosis of Anastomotic Leakage After Colorectal Surgery: Italian ColoRectal Anastomotic Leakage Study Group.

Status unknown Last updated 18 June 2018

What this trial tests

trial testing Dutch score in Anastomotic Leak in 1,131 participants. Status unknown.

Timeline

4 September 2017

Primary endpoint
31 August 2018

30 September 2018

Quick facts

Lead sponsor	Ospedale C & G Mazzoni
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	1,131
Start date	4 September 2017
Primary completion	31 August 2018
Estimated completion	30 September 2018
Sites	18 locations across Italy

Drugs / interventions tested

Dutch score
Serum C-reactive Protein
serum Procalcitonin

Conditions studied

Anastomotic Leak — all drugs for Anastomotic Leak →
Colorectal Surgery — all drugs for Colorectal Surgery →

Sponsor

Ospedale C & G Mazzoni

Who can join

Eligibility, any sex, with Anastomotic Leak or Colorectal Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Prospective evaluation of early diagnosis of anastomotic leak after colorectal resection through evaluation of Dutch leakage score, serum C-reactive protein and serum Procalcitonin

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Anastomotic leakage after elective colorectal surgery: a prospective multicentre observational study on use of the Dutch leakage score, serum procalcitonin and serum C-reactive protein for diagnosis.
Italian ColoRectal Anastomotic Leakage (iCral) Study Group. · · 2020 · cited 39× · PMID 32134216 · DOI 10.1002/bjs5.50269
Risk factors for adverse events after elective colorectal surgery: beware of blood transfusions.
Italian ColoRectal Anastomotic Leakage (iCral) study group. · · 2020 · cited 12× · PMID 32399595 · DOI 10.1007/s13304-020-00753-2
Early diagnosis of anastomotic leakage after colorectal surgery by the Dutch leakage score, serum procalcitonin and serum C-reactive protein: study protocol of a prospective multicentre observational study by the Italian ColoRectal Anastomotic Leakage (iC.
Benedetti M, Ciano P, Pergolini I, Ciotti S, et al · · 2019 · cited 10× · PMID 30771794
Colorectal surgery in Italy: a snapshot from the iCral study group.
Italian ColoRectal Anastomotic Leakage (iCral) study group. · · 2019 · cited 10× · PMID 30747374 · DOI 10.1007/s13304-018-00612-1
Management and 1-year outcomes of anastomotic leakage after elective colorectal surgery.
Italian ColoRectal Anastomotic Leakage (iCral) study group, Borghi F, Migliore M, Cianflocca D, et al · · 2021 · cited 7× · PMID 33118101 · DOI 10.1007/s00384-020-03777-7

Verify or expand the search:

Other recruiting trials for Anastomotic Leak

Currently open trials in the same condition.

NCT07449208 — Registry Study of People Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak · recruiting
NCT07351071 — Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Res · NA · recruiting
NCT07144683 — Anastomotic Leakage After Colorectal Surgery. · recruiting
NCT07036588 — PARLAR-02 Trial：Modified Transanal Drainage Tube Use for Preventing Anastomotic Leakage · NA · recruiting
NCT06553261 — Anastomotic Leakage in Right Colectomy · recruiting

Other Ospedale C & G Mazzoni trials

Trials by the same sponsor.

NCT05167799 — Cardiac Contractility Modulation Therapy in Amyloid Cardiomyopathy Patients With Heart Failure · unknown
NCT04397627 — ERAS Program Items Adherence, PROMs and RIOT After Colorectal Surgery · unknown
NCT03771456 — Anastomotic Leakage and Enhanced Recovery Pathways After Colorectal Surgery · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03560180 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ospedale C & G Mazzoni
Last refreshed: 18 June 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03560180.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing