NCT03546647 is a NA clinical trial of Dailies Aqua Comfort Plus Toric in Astigmatism, sponsored by University of Houston.

Who is sponsoring NCT03546647?

NCT03546647 is sponsored by University of Houston.

What drugs are being tested in NCT03546647?

Interventions in NCT03546647: Dailies Aqua Comfort Plus Toric, Dailies Aqua Comfort Plus Sphere.

What condition does NCT03546647 study?

NCT03546647 studies Astigmatism.

Is NCT03546647 still recruiting?

NCT03546647 is currently completed. Last updated 7 June 2021.

Are results published for NCT03546647?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2021-06-07 · How we verify

NCT03546647

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Toric Contact Lens Performance Study

Completed NA Results posted Last updated 7 June 2021

What this trial tests

NA trial testing Dailies Aqua Comfort Plus Toric in Astigmatism in 35 participants. Completed in 21 December 2018.

Timeline

18 June 2018

Primary endpoint
21 December 2018

21 December 2018

Quick facts

Lead sponsor	University of Houston
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	35
Start date	18 June 2018
Primary completion	21 December 2018
Estimated completion	21 December 2018
Sites	1 location across United States

Drugs / interventions tested

Dailies Aqua Comfort Plus Toric
Dailies Aqua Comfort Plus Sphere

Conditions studied

Astigmatism — all drugs for Astigmatism →

Sponsor

University of Houston

Who can join

Adults 18 to 39, any sex, with Astigmatism. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Near Visual LogMAR Acuity Primary · 10 +/- 2 days

High contrast LogMAR visual acuity was assessed at 40 cm using the M\&S Clinical Trial Suite system (Niles, Illinois, USA). The system was calibrated according to the manufacturer's directions every day, prior to use. Testing was performed binocularly. The test started at 20/200 and continued until three letters were missed on a line.

Group	Value	95% CI
Toric	-0.09	± 0.07
Sphere	-0.02	± 0.09

Adverse events — posted to ClinicalTrials.gov

Time frame: 10 ± 2 days for each intervention. Reporting threshold: 0%. Adverse-event reports describe events observed during the trial — not all are caused by the drug.

Toric

Serious: 0/34 (0%)

Deaths: 0/34

Sphere

Serious: 0/34 (0%)

Deaths: 0/34

Other adverse events (1 terms — click to expand)

Reaction	System	Toric	Sphere
Keratitis	Eye disorders	—	—

Data from ClinicalTrials.gov NCT03546647 adverse events section.

Sponsor's own description

This study seeks to quantify digital visual performance and subjective visual acceptance of toric contact lenses as compared to spherical lenses in low to moderate astigmatic patients.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Astigmatism

Currently open trials in the same condition.

NCT07303920 — Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day · NA · recruiting
NCT07284966 — Comfort and Vision With TOTAL30 Multifocal Lenses · recruiting
NCT07078799 — Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery · NA · recruiting
NCT07084844 — Patient Reported Outcomes With WaveLight Plus LASIK · recruiting
NCT07140653 — Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery · Phase 4 · recruiting

Other University of Houston trials

Trials by the same sponsor.

NCT07024992 — Enhancing Smoking Cessation for African American People Everywhere · Phase 2 · not yet recruiting
NCT07025772 — Shaping Habitual Impulses For a Tobacco-free Style · NA · recruiting
NCT07007195 — Smart Olfaction App to Reduce Relapse · EARLY_PHASE1 · not yet recruiting
NCT06918821 — Reducing Obesity Through Play Among Toddlers: Tiny Steps to Health (TSHS) Study · NA · recruiting
NCT07227220 — Summer Youth Employment Programs for Health Promotion · EARLY_PHASE1 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03546647 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Houston
Last refreshed: 7 June 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03546647.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing