NCT03536520 is a Phase 4 clinical trial of ACETAZOLAMIDE oral capsule in Altitude Hypoxia, sponsored by University of Zurich.

Who is sponsoring NCT03536520?

NCT03536520 is sponsored by University of Zurich.

What drugs are being tested in NCT03536520?

Interventions in NCT03536520: ACETAZOLAMIDE oral capsule, Placebo oral capsule.

What condition does NCT03536520 study?

NCT03536520 studies Altitude Hypoxia.

Is NCT03536520 still recruiting?

NCT03536520 is currently completed. Last updated 12 October 2021.

Last reviewed 2021-10-12 · How we verify

NCT03536520

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Acetazolamide on Visuo-motor Learning in Lowlanders Older Than 40 Years at Altitude

Completed Phase 4 Last updated 12 October 2021

What this trial tests

Phase 4 trial testing ACETAZOLAMIDE oral capsule in Altitude Hypoxia in 59 participants. Completed in 2 August 2018.

Timeline

15 May 2018

Primary endpoint
2 August 2018

2 August 2018

Quick facts

Lead sponsor	University of Zurich
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	59
Start date	15 May 2018
Primary completion	2 August 2018
Estimated completion	2 August 2018
Sites	1 location across Kyrgyzstan

Drugs / interventions tested

ACETAZOLAMIDE oral capsule — full drug profile →
Placebo oral capsule

Conditions studied

Altitude Hypoxia — all drugs for Altitude Hypoxia →

Sponsor

University of Zurich

Who can join

Adults 40 to 75, any sex, with Altitude Hypoxia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Randomized, placebo controlled trial evaluating the effect of acetazolamide on visuo-motor learning performance in lowlanders older than 40 years travelling from 760 m to 3'100 m.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effect of acetazolamide on visuomotor performance at high altitude in healthy people 40 years of age or older-RCT.
Reiser AE, Furian M, Lichtblau M, Buergin A, et al · · 2023 · cited 4× · PMID 36662903 · DOI 10.1371/journal.pone.0280585

Verify or expand the search:

Other trials of ACETAZOLAMIDE oral capsule

Trials testing the same drug.

NCT07517068 — The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High Altitude · EARLY_PHASE1 · active not recruiting
NCT03540914 — Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders Older Than 40 Years at Altitude. · Phase 4 · unknown
NCT03537924 — Effect of Acetazolamide on Right Heart Function During Exercise in Lowlanders Older Than 40 Years at Altitude · Phase 4 · unknown
NCT03539367 — Effect of Acetazolamide on Lung Water Content by Ultrasound in Lowlanders Older Than 40 Years at Altitude · Phase 4 · unknown
NCT03540901 — Effect of Acetazolamide on Lung Water Content by Ultrasound in Patients With Respiratory Disease at Altitude · Phase 4 · completed

Other recruiting trials for Altitude Hypoxia

Currently open trials in the same condition.

NCT05500014 — Effect of Altitude on Iron Absorption in Iron Depleted Women · NA · active not recruiting

Other University of Zurich trials

Trials by the same sponsor.

NCT07485699 — Soy Processing and Food Allergy · NA · not yet recruiting
NCT07516912 — Evaluation of Free STI Testing Pilot Projects in Lucerne and Zurich, Switzerland · not yet recruiting
NCT07473115 — Individualized Analgesia in the Intensive Care Unit With a New Pain Assessment Bundle and Protocolized Analgesia Adjustm · not yet recruiting
NCT07524023 — Emotional-distress-based Integrated Care Programme in Patients With Stable COPD · NA · recruiting
NCT06481982 — Value of Advanced MRI Techniques in the Assessment of Endometriosis · withdrawn

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03536520 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Zurich
Last refreshed: 12 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03536520.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing