NCT03536065 (ORIOLES) is a NA clinical trial of Opioid Reduction Intervention in Prostate Cancer, sponsored by Johns Hopkins University.

Who is sponsoring NCT03536065?

NCT03536065 is sponsored by Johns Hopkins University.

What drugs are being tested in NCT03536065?

Interventions in NCT03536065: Opioid Reduction Intervention, Current Care.

What condition does NCT03536065 study?

NCT03536065 studies Prostate Cancer, Opioid Use.

Is NCT03536065 still recruiting?

NCT03536065 is currently completed. Last updated 28 July 2020.

Last reviewed 2020-07-28 · How we verify

NCT03536065: ORIOLES

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Post-Discharge Opioid Reduction Intervention for Open, Laparoscopic, and Endoscopic Surgery

Completed NA Last updated 28 July 2020

What this trial tests

NA trial testing Opioid Reduction Intervention in Prostate Cancer in 443 participants. Completed in 1 March 2019.

Timeline

1 August 2017

Primary endpoint
1 March 2019

1 March 2019

Quick facts

Lead sponsor	Johns Hopkins University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	sequential
Masking	none
Primary purpose	prevention
Enrollment	443
Start date	1 August 2017
Primary completion	1 March 2019
Estimated completion	1 March 2019
Sites	1 location across United States

Drugs / interventions tested

Opioid Reduction Intervention
Current Care

Conditions studied

Prostate Cancer — all drugs for Prostate Cancer →
Opioid Use — all drugs for Opioid Use →

Sponsor

Johns Hopkins University

Who can join

Adults 18 to 100, male only, with Prostate Cancer or Opioid Use. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

ORIOLES is a non-randomized, pre-post intervention study designed to improve quality of opioid prescribing and use after discharge for patients undergoing urologic surgery. The study will initially focus on a pre-defined cohort of patients undergoing radical prostatectomy. After the predefined study period for the pre-intervention arm, a three-part intervention is employed to assess the effect on opioid prescribing and use in the post-intervention arm. Pending results, the intervention may be applied to all surgeries in the department for routine clinical care.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Prostate Cancer

Currently open trials in the same condition.

NCT06960798 — Characterizing the Genomic Landscape of Prostate Cancer in Native American Populations (NAT-Geno) · recruiting
NCT07237269 — Abi/Pred + ADT vs ADT in PSMA-Positive, Conventionally Node-Negative Prostate Cancer · Phase 2 · recruiting
NCT07234981 — PSMA-PET Guided De-escalation of Salvage Radiation Treatment in Recurrent Prostate Cancer · Phase 2 · recruiting
NCT07027124 — Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Ris · Phase 2 · recruiting
NCT07426094 — PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate · Phase 2, PHASE3 · recruiting

Other Johns Hopkins University trials

Trials by the same sponsor.

NCT06236542 — Tracheostomy Robotics and Cutting-edge Health Education for Airway Safety · NA · not yet recruiting
NCT07532252 — Daridorexant for Alcohol Use Disorder · Phase 2 · not yet recruiting
NCT06687655 — Impact of Exogenous Ketones on Sleep Apnea · Phase 1, PHASE2 · not yet recruiting
NCT07079111 — 3D Printed Occlusal Splints for Intraoperative Use · NA · not yet recruiting
NCT02998502 — The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03536065 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
Last refreshed: 28 July 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03536065.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing