Last reviewed · How we verify
NCT03524924: ESCAPE
Edoxaban and Frailty in Senior Individuals
trial in Atrial Fibrillation in 180 participants. Completed in 31 March 2021.
14 January 2021
Quick facts
| Lead sponsor | University of Padova |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 180 |
| Start date | 7 January 2018 |
| Primary completion | 14 January 2021 |
| Estimated completion | 31 March 2021 |
| Sites | 1 location across Italy |
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
Sponsor
University of Padova
Who can join
80 and older, any sex, with Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Edoxaban, has shown in clinical registration trials a significant reduction of major bleeding compared to warfarin, especially in elderly patients. Efficacy and safety of edoxaban will be assessed in a cohort of very elderly patients (≥80 years of age) with NVAF. A secondary analysis will correlate outcomes with frailty defined according to SHARE-FI (not-frail, pre-frail or frail).
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Very Elderly Patients With Atrial Fibrillation Treated With Edoxaban: Impact of Frailty on Outcomes.
Denas G, Zoppellaro G, Granziera S, Pagliani L, et al · · 2023 · cited 4× · PMID 38939480 · DOI 10.1016/j.jacadv.2023.100569 -
Very Elderly Patients With Atrial Fibrillation Treated With Edoxaban : Impact of Frailty on Outcomes
Denas G, Zoppellaro G, Granziera S, Pagliani L, et al · · 2023
Verify or expand the search:
- PubMed search for NCT03524924
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Padova trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03524924 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Padova
- Last refreshed: 10 August 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03524924.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing