Last reviewed · How we verify
NCT03518372: MONITOR
Myocardial Injury and Intraoperative Tissue Oximetry in Patients Undergoing Spine Surgery
trial in Hypoxia in 70 participants. Completed in 24 July 2018.
24 July 2018
Quick facts
| Lead sponsor | University of California, San Francisco |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 70 |
| Start date | 2 January 2018 |
| Primary completion | 24 July 2018 |
| Estimated completion | 24 July 2018 |
| Sites | 1 location across United States |
Conditions studied
- Hypoxia — all drugs for Hypoxia →
- Myocardial Injury — all drugs for Myocardial Injury →
- Surgery--Complications — all drugs for Surgery--Complications →
Sponsor
University of California, San Francisco
Who can join
18 and older, any sex, with Hypoxia or Myocardial Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Myocardial injury after non-cardiac surgery (MINS) is common in patients undergoing major surgery. Many of the events are undetected and associated with a high 30-day mortality risk. Knowledge of which perioperative factors that predicts MINS is lacking. Decrease in tissue oxygenation (StO2) is common in patients undergoing major spine surgery and is associated with postoperative complications in these patients. However, an association between decrease in tissue oxygenation and MINS has not been examined. This group of patients may have other potential predictors of postoperative complications that the study group would like to investigate. In this observational cohort study, we will include 70 patients undergoing major spine surgery at University of California San Francisco. The primary hypothesis is that decrease in intraoperative tissue oxygenation is associated with postoperative myocardial injury.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Association between tissue oxygenation and myocardial injury in patients undergoing major spine surgery: a prospective cohort study.
Bernholm KF, Meyhoff CS, Bickler P. · · 2021 · cited 1× · PMID 34535471 · DOI 10.1136/bmjopen-2020-044342
Verify or expand the search:
- PubMed search for NCT03518372
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03518372 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, San Francisco
- Last refreshed: 16 June 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03518372.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing