NCT03518359 (ESRT-R) is a NA clinical trial of Enhanced Stress Resilience Training (ESRT) in Stress, sponsored by University of California, San Francisco.

Who is sponsoring NCT03518359?

NCT03518359 is sponsored by University of California, San Francisco.

What drugs are being tested in NCT03518359?

Interventions in NCT03518359: Enhanced Stress Resilience Training (ESRT), Active Control.

What condition does NCT03518359 study?

NCT03518359 studies Stress, Mindfulness, Cognitive Change.

Is NCT03518359 still recruiting?

NCT03518359 is currently completed. Last updated 24 February 2022.

Last reviewed 2022-02-24 · How we verify

NCT03518359: ESRT-R

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Enhanced Stress Resilience Training for Residents

Completed NA Last updated 24 February 2022

What this trial tests

NA trial testing Enhanced Stress Resilience Training (ESRT) in Stress in 45 participants. Completed in 30 June 2021.

Timeline

13 June 2018

Primary endpoint
30 June 2021

30 June 2021

Quick facts

Lead sponsor	University of California, San Francisco
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	45
Start date	13 June 2018
Primary completion	30 June 2021
Estimated completion	30 June 2021
Sites	1 location across United States

Drugs / interventions tested

Enhanced Stress Resilience Training (ESRT)
Active Control — full drug profile →

Conditions studied

Stress — all drugs for Stress →
Mindfulness — all drugs for Mindfulness →
Cognitive Change — all drugs for Cognitive Change →

Sponsor

University of California, San Francisco

Who can join

Adults 18 to 64, any sex, with Stress or Mindfulness. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Burnout and overwhelming stress are growing issues in medicine and are associated with mental illness, performance deficits and diminished patient care. Among surgical trainees, high dispositional mindfulness decreases these risks by 75% or more, and formal mindfulness training has been shown feasible and acceptable. In other high-stress populations formal mindfulness training has improved well-being, stress, cognition and performance, yet the ability of such training to mitigate stress and burnout across medical specialties, or to affect improvements in the cognition and performance of physicians, remains unknown. To address these gaps and thereby promote the wider adoption of contemplative practices within medical training, investigators have developed Enhanced Stress Resilience Training, a modified form of MBSR - streamlined, tailored and contextualized for physicians and trainees. Investigators propose to test Enhanced Stress Resilience Training (ESRT), versus active control and residency-as-usual, in surgical and non-surgical residents evaluated for well-being, cognition and performance changes at baseline, post-intervention and six-month follow-up.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Psychological interventions to foster resilience in healthcare professionals.
Kunzler AM, Helmreich I, Chmitorz A, König J, et al · · 2020 · cited 221× · PMID 32627860 · DOI 10.1002/14651858.cd012527.pub2
Individual-level interventions for reducing occupational stress in healthcare workers.
Tamminga SJ, Emal LM, Boschman JS, Levasseur A, et al · · 2023 · cited 49× · PMID 37169364 · DOI 10.1002/14651858.cd002892.pub6

Verify or expand the search:

Other recruiting trials for Stress

Currently open trials in the same condition.

NCT07485790 — The Effects of Yoga on Pregnant Women · NA · recruiting
NCT07469527 — Effects of Feel Free® Classic Tonic on Stress and Pharmacokinetics in Healthy Adults · NA · recruiting
NCT07387107 — Decreasing Stress Via Virtual Reality and Binaural Beats in Non-Clinical Adults · NA · recruiting
NCT07240792 — Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Student · NA · recruiting
NCT07518056 — Relationships Between Nomophobia Levels and Perceived Stress, Body Image and Food Addiction Among University Students · recruiting

Other University of California, San Francisco trials

Trials by the same sponsor.

NCT05284773 — Screening for Acute Malnutrition · NA · withdrawn
NCT04634851 — Video Home Visits for Dietary Counselling · NA · not yet recruiting
NCT06065670 — Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a M · Phase 1, PHASE2 · not yet recruiting
NCT07534098 — Intervention for Hearing Health Among Native Americans · NA · not yet recruiting
NCT06960421 — Exercise-based Frailty Intervention in Lung Transplantation (XFIT) · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03518359 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of California, San Francisco
Last refreshed: 24 February 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03518359.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing