NCT03509792

Simple Cognitive Task After Trauma

Completed NA Last updated 2 September 2022

What this trial tests

NA trial testing Simple cognitive task in Post-traumatic Stress Disorders in 42 participants. Completed in 20 December 2019.

Timeline

11 January 2019

Primary endpoint
12 July 2019

20 December 2019

Quick facts

Lead sponsor	Karolinska Institutet
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	42
Start date	11 January 2019
Primary completion	12 July 2019
Estimated completion	20 December 2019
Sites	1 location across Sweden

Drugs / interventions tested

• Simple cognitive task
• Attention placebo

Conditions studied

• Post-traumatic Stress Disorders — all drugs for Post-traumatic Stress Disorders →

Sponsor

Karolinska Institutet

Who can join

18 and older, any sex, with Post-traumatic Stress Disorders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This research study is designed to investigate the effects of a simple cognitive task (a memory cue following by playing the computer game "Tetris") on intrusive memories ("flashbacks") and other symptoms after a traumatic event. Patients presenting to a hospital emergency department soon after a traumatic event will be randomly allocated to either the simple cognitive task intervention or control. Participants will be followed up at one week and one month, and where possible 3 and 6 months. It is predicted that participants given the simple cognitive task intervention will develop fewer intrusive memories and less severe clinical symptoms than those who are not. This will inform the potential future development of a simple technique to prevent distressing psychological symptoms after a traumatic event. Implementation aspects in a new hospital context will also be explored. Patients use their smartphone for part of the intervention in the study.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Reducing intrusive memories after trauma via a brief cognitive task intervention in the hospital emergency department: an exploratory pilot randomised controlled trial.
   Kanstrup M, Singh L, Göransson KE, Widoff J, et al · · 2021 · cited 44× · PMID 33431807 · DOI 10.1038/s41398-020-01124-6
2. A simple cognitive task intervention to prevent intrusive memories after trauma in patients in the Emergency Department: A randomized controlled trial terminated due to COVID-19.
   Kanstrup M, Singh L, Göransson KE, Gamble B, et al · · 2021 · cited 6× · PMID 33971951 · DOI 10.1186/s13104-021-05572-1