NCT03486145

Effect of Nitrate-rich Fruit and Vegetable Supplement on Blood Pressure

Completed NA Last updated 3 April 2018

What this trial tests

NA trial testing fruit and vegetable juice supplement in High Blood Pressure in 57 participants. Completed in 30 March 2016.

Timeline

16 November 2015

Primary endpoint
30 March 2016

30 March 2016

Quick facts

Lead sponsor	Arizona State University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	57
Start date	16 November 2015
Primary completion	30 March 2016
Estimated completion	30 March 2016
Sites	1 location across United States

Drugs / interventions tested

• fruit and vegetable juice supplement
• Placebo

Conditions studied

• High Blood Pressure — all drugs for High Blood Pressure →
• Flow Mediated Dilation — all drugs for Flow Mediated Dilation →

Sponsor

Arizona State University

Who can join

Adults 18 to 40, any sex, with High Blood Pressure or Flow Mediated Dilation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It is hypothesized that the daily supplementation of a nitrate-rich, two-ounce fruit and vegetable energy supplement (Isagenix International LLC) by healthy young adults with a would increase circulating nitrates and improve cardiovascular parameters compared to a nitrate-deficient placebo (prune juice).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Nitrate-Rich Fruit and Vegetable Supplement Reduces Blood Pressure in Normotensive Healthy Young Males without Significantly Altering Flow-Mediated Vasodilation: A Randomized, Double-Blinded, Controlled Trial.
   Sweazea KL, Johnston CS, Miller B, Gumpricht E. · · 2018 · cited 17× · PMID 30305961 · DOI 10.1155/2018/1729653