Last reviewed · How we verify
NCT03472872
A Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache
Phase 4 trial testing Ketorolac in Headache. Withdrawn.
14 June 2020
Quick facts
| Lead sponsor | Corewell Health South |
|---|---|
| Phase | Phase 4 |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Start date | 5 September 2017 |
| Primary completion | 14 June 2020 |
| Estimated completion | 14 June 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Ketorolac (KETOROLAC) — full drug profile →
- Acetaminophen (Paracetamol) — full drug profile →
Conditions studied
- Headache — all drugs for Headache →
Sponsor
Corewell Health South — full company profile →
Who can join
Adults 18 to 65, any sex, with Headache. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized, double-blind trial will compare the clinical efficacy of IV acetaminophen to that of IV ketorolac as adjuncts to standard therapy (prochlorperazine and diphenhydramine) in the treatment of patients presenting to the emergency department with chief complaint of "headache" or variants thereof.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03472872
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Ketorolac
Trials testing the same drug.
- NCT07487246 — Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement · Phase 2 · not yet recruiting
- NCT07430085 — Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA · Phase 4 · not yet recruiting
- NCT06994442 — Optimizing Pain Treatment in Children On Mechanical Ventilation · Phase 3 · recruiting
- NCT06968806 — Study on Ketorolac for Improving Outcomes and Prognosis in Patients With Stanford Type A Aortic Dissection · Phase 3 · recruiting
- NCT06973785 — Non-Narcotic Pain Control After ACL Reconstruction · Phase 3 · recruiting
Other recruiting trials for Headache
Currently open trials in the same condition.
- NCT07487649 — Treatment Response in Patients With Medication-Overuse Headache · recruiting
- NCT07097792 — Concussion Recovery and Support Program · NA · recruiting
- NCT06225817 — Placebo Impacts Sleep and Pain Modulation in Chronic Pain · NA · recruiting
- NCT06310200 — Sphenopalatine Ganglion Block and Cold Induced Headaches · Phase 1 · active not recruiting
- NCT07404956 — THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES · NA · recruiting
Other Corewell Health South trials
Trials by the same sponsor.
- NCT06955013 — Ultrasound to View Abdominal Wall Muscle Layers · recruiting
- NCT06570395 — Osteopathic Manipulative Treatment in the Third Trimester of Pregnancy · terminated
- NCT06155643 — EKO SENSORA: Detecting Clinically Significant Murmurs · NA · recruiting
- NCT05367336 — Platelet Reactivity With Fentanyl, Morphine, or no Narcotic · Phase 2 · terminated
- NCT05473897 — Cooling Helmets to Decrease Concussion Symptoms · NA · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03472872 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Corewell Health South
- Last refreshed: 29 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03472872.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing