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NCT03449888: ArmCrank
Arm Exercise Versus Pharmacologic Stress Testing for Clinical Outcome
trial testing Regadenoson myocardial perfusion imaging stress test in Veterans Referred to the St. Louis VAMC Stress Tes in 133 participants. Terminated before completion.
5 February 2021
Quick facts
| Lead sponsor | VA Office of Research and Development |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 133 |
| Start date | 1 July 2018 |
| Primary completion | 5 February 2021 |
| Estimated completion | 5 February 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Regadenoson myocardial perfusion imaging stress test
- Arm exercise electrocardiographic stress test
- Treadmill electrocardiographic stress test
- Coronary artery calcium score and cardiac computed tomographic angiography
Conditions studied
- Veterans Referred to the St. Louis VAMC Stress Tes — all drugs for Veterans Referred to the St. Louis VAMC Stress Tes →
Sponsor
VA Office of Research and Development — full company profile →
Who can join
Adults 21 to 100, any sex, with Veterans Referred to the St. Louis VAMC Stress Tes. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a 5-year clinical trial to evaluate whether arm exercise electrocardiographic (ECG) stress testing without or with coronary artery calcium scoring (-/+ CAC) is non-inferior to treadmill ECG stress testing -/+ CAC and pharmacologic myocardial perfusion imaging as an initial evaluation to detect obstructive coronary artery disease, determined by cardiac computed tomographic angiography (CTA) and to predict clinical outcome, defined by a primary clinical endpoint of the composite of cardiovascular (CV) mortality, myocardial infarction, and 90-day post-stress test coronary artery revascularization and secondary clinical endpoints of all-cause mortality and CV mortality.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03449888
- Europe PMC full search
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03449888 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by VA Office of Research and Development
- Last refreshed: 17 February 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03449888.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing