NCT03449849 is a NA clinical trial of Base Diet in Healthy Volunteers, sponsored by USDA Beltsville Human Nutrition Research Center.

Who is sponsoring NCT03449849?

NCT03449849 is sponsored by USDA Beltsville Human Nutrition Research Center.

What drugs are being tested in NCT03449849?

Interventions in NCT03449849: Base Diet, Kale Treatment.

What condition does NCT03449849 study?

NCT03449849 studies Healthy Volunteers.

Is NCT03449849 still recruiting?

NCT03449849 is currently completed. Last updated 12 September 2018.

Last reviewed 2018-09-12 · How we verify

NCT03449849

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Kale Consumption on Human Xenobiotic Metabolizing Enzymes

Completed NA Last updated 12 September 2018

What this trial tests

NA trial testing Base Diet in Healthy Volunteers in 27 participants. Completed in 1 August 2018.

Timeline

18 April 2018

Primary endpoint
1 August 2018

1 August 2018

Quick facts

Lead sponsor	USDA Beltsville Human Nutrition Research Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	other
Enrollment	27
Start date	18 April 2018
Primary completion	1 August 2018
Estimated completion	1 August 2018
Sites	1 location across United States

Drugs / interventions tested

Base Diet
Kale Treatment

Conditions studied

Healthy Volunteers — all drugs for Healthy Volunteers →

Sponsor

USDA Beltsville Human Nutrition Research Center

Who can join

Adults 21 to 75, any sex, with Healthy Volunteers. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary objective of this study is to determine how daily consumption of kale changes the activity of human xenobiotic metabolizing enzymes. Secondary objectives are to measure absorption and metabolism of kale phytonutrients, and to determine how kale consumption affects gene expression related to metabolism and lipid measures associated with cardiovascular health.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Systematic Review on the Metabolic Interest of Glucosinolates and Their Bioactive Derivatives for Human Health.
Costa-Pérez A, Núñez-Gómez V, Baenas N, Di Pede G, et al · · 2023 · cited 19× · PMID 36986155 · DOI 10.3390/nu15061424

Verify or expand the search:

Other recruiting trials for Healthy Volunteers

Currently open trials in the same condition.

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NCT07499050 — A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants With Obesity · Phase 1 · recruiting
NCT07342114 — A Dose-Escalation Study of RO7875913 in Healthy Participants · Phase 1 · recruiting

Other USDA Beltsville Human Nutrition Research Center trials

Trials by the same sponsor.

NCT07146958 — Soup and Bread Recipe Impacts on Ingestive Behavior · NA · recruiting
NCT06771765 — Soup Meal Satiety Study · NA · completed
NCT05589389 — Meat and Dietary Pattern Study · NA · active not recruiting
NCT03779971 — Energy Value of Lentils and Chickpeas · NA · completed
NCT04104581 — Measuring Daily Grain Intake Study · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03449849 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by USDA Beltsville Human Nutrition Research Center
Last refreshed: 12 September 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03449849.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing