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NCT07499050
A Study of Multiple Doses of Orally Administered RO7795081 in Otherwise Healthy Chinese Adult Participants With Obesity or Overweight
Phase 1 trial testing RO7795081 in Healthy Volunteers in 30 participants. Currently enrolling.
29 December 2026
Quick facts
| Lead sponsor | Hoffmann-La Roche |
|---|---|
| Phase | Phase 1 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 30 |
| Start date | 30 March 2026 |
| Primary completion | 29 December 2026 |
| Estimated completion | 29 December 2026 |
| Sites | 2 locations across China |
Drugs / interventions tested
- RO7795081 — full drug profile →
- Placebo
Conditions studied
- Healthy Volunteers — all drugs for Healthy Volunteers →
- Overweight or Obesity — all drugs for Overweight or Obesity →
Sponsor
Hoffmann-La Roche — full company profile →
Who can join
Adults 18 to 65, any sex, with Healthy Volunteers or Overweight or Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is an investigator- and participant-blind, randomized, placebo-controlled, parallel-group, Phase I study evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple doses of orally administered RO7795081 in otherwise healthy Chinese adult participants with obesity or overweight.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07499050
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of RO7795081
Trials testing the same drug.
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- NCT07081958 — A Study Evaluating the Effect of Daily Oral RO7795081 in Participants With Obesity or Overweight With at Least One Weigh · Phase 2 · active not recruiting
- NCT06982131 — A Study Investigating the Safety of RO7795081 and the Effect of RO7795081 on How the Body Processes Pitavastatin and Ros · Phase 1 · recruiting
- NCT06809608 — A Study Investigating the Effect of Different Approved Medications on How the Body Processes the Study Compound RO779508 · Phase 1 · completed
Other recruiting trials for Healthy Volunteers
Currently open trials in the same condition.
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Other Hoffmann-La Roche trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07499050 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hoffmann-La Roche
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07499050.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing