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NCT03448614
Skull Base Reconstruction After Endonasal Cranio-endoscopic Resection Using Autologus Grafts
trial in Skull Base Neoplasms in 50 participants. Status unknown.
1 January 2019
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 January 2018 |
| Primary completion | 1 January 2019 |
| Estimated completion | 1 January 2020 |
| Sites | 1 location across Egypt |
Conditions studied
- Skull Base Neoplasms — all drugs for Skull Base Neoplasms →
Sponsor
Assiut University
Who can join
Eligibility, any sex, with Skull Base Neoplasms. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Endonasal endoscopic approach to the skull base has been expanded in the last several years owing to advances in the radiological aspect that provided a better evaluation of the lesions and the surrounding structures, technological advances that include angled endoscope, development of high-resolution cameras, high definition monitors and navigation systems and better anatomical experience. The endoscopic endonasal approach now provides access to frontal sinus to the second cervical vertebra in the sagittal plane and from the sella to the jugular foramen in the coronal plane. Endoscopic resection of large skull base tumors results in large defect for which repair is a challenge. Several factors besides the size of the defect should be considered during skull base repair as CSF leak, CSF pressure, history or need for future radiotherapy, lack of support and local tissue vascularity. The aim of this study is to Provide an algorithmic approach for skull base reconstruction after endonasal cranio-endoscopic resection using autologous grafts according to the extent of resection, skull base defect size, the presence of CSF leak, CSF pressure and local tissue vascular
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03448614
- Europe PMC full search
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Related trials
Other recruiting trials for Skull Base Neoplasms
Currently open trials in the same condition.
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- NCT05607888 — Prospective Study of Sinonasal and Skull-base Tumours Management · recruiting
Other Assiut University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03448614 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 28 February 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03448614.
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