NCT03448562 (STABLE-SR_II) is a NA clinical trial of CPVI in Atrial Fibrillation, sponsored by The First Affiliated Hospital with Nanjing Medical University.

Who is sponsoring NCT03448562?

NCT03448562 is sponsored by The First Affiliated Hospital with Nanjing Medical University.

What drugs are being tested in NCT03448562?

Interventions in NCT03448562: CPVI, STABLE-SR.

What condition does NCT03448562 study?

NCT03448562 studies Atrial Fibrillation.

Is NCT03448562 still recruiting?

NCT03448562 is currently status unknown. Last updated 11 February 2020.

Last reviewed 2020-02-11 · How we verify

NCT03448562: STABLE-SR_II

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

CPVI Alone Versus. CPVI Plus Electrophysiological Substrate Ablation in the LA During SR for the Treatment of Non-PAF

Status unknown NA Last updated 11 February 2020

What this trial tests

NA trial testing CPVI in Atrial Fibrillation in 300 participants. Status unknown.

Timeline

1 April 2018

Primary endpoint
30 September 2020

30 September 2020

Quick facts

Lead sponsor	The First Affiliated Hospital with Nanjing Medical University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	300
Start date	1 April 2018
Primary completion	30 September 2020
Estimated completion	30 September 2020
Sites	1 location across China

Drugs / interventions tested

CPVI
STABLE-SR

Conditions studied

Atrial Fibrillation — all drugs for Atrial Fibrillation →

Sponsor

The First Affiliated Hospital with Nanjing Medical University

Who can join

Adults 18 to 80, any sex, with Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary objective of this investigation is to compare the efficacy of two different AF ablation strategies in patients with non-paroxysmal AF: CPVI plus electrophysiologic substrate ablation in the left atrium during sinus rhythm (STABLE-SR) and CPVI alone.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Circumferential Pulmonary Vein Isolation Plus Low-Voltage Area Modification in Persistent Atrial Fibrillation: The STABLE-SR-II Trial.
Yang G, Zheng L, Jiang C, Fan J, et al · · 2022 · cited 97× · PMID 35863814 · DOI 10.1016/j.jacep.2022.03.012
Persistent atrial fibrillation with left atrial low-voltage area: who benefit from additional modification?
Zhang H, Chen N, Bian Q, Yuan M, et al · · 2025 · PMID 40327545 · DOI 10.1093/europace/euaf095

Verify or expand the search:

Other trials of CPVI

Trials testing the same drug.

NCT06499818 — CPVI Alone Versus CPVI Plus Low-Voltage Areas Ablation During SR Versus CPVI Plus Low-Voltage Areas Ablation During AF f · NA · not yet recruiting
NCT03998956 — High-density Mapping-guided bOx Isolation and subsTrate Ablation · NA · unknown

Other recruiting trials for Atrial Fibrillation

Currently open trials in the same condition.

NCT07429214 — A Study of VARIPULSE Catheter and TRUPULSE Generator With VARIPULSE Pro Software in Participants With PAF or PsAF · NA · recruiting
NCT07271238 — Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures · NA · recruiting
NCT07388108 — Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery. · recruiting
NCT07428967 — AV Node Ablation and CONDUCTion System Pacing for Atrial Fibrillation With Preserved Left Ventricular Function · NA · recruiting
NCT06650995 — AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure · NA · recruiting

Other The First Affiliated Hospital with Nanjing Medical University trials

Trials by the same sponsor.

NCT07377981 — An Exploratory Study of the Efficacy and Safety of Esketamine and Dexmedetomidine in Non-Intubated ICU Patients With Hyp · Phase 4 · not yet recruiting
NCT07523789 — Comparison of Chemotherapy and Immunotherapy in Neoadjuvant Therapy for TNBC · not yet recruiting
NCT07464756 — SHR-1701 With or Without Apatinib in Combination With Chemotherapy as Neoadjuvant Therapy for Gastric Cancer · Phase 2 · not yet recruiting
NCT07482826 — Full-Endoscopic Decompression vs. Endoscopic Lumbar Fusion for Middle-Aged and Older Adults With Spinal Stenosis · NA · not yet recruiting
NCT07558863 — Effect of GLP-1RA on Cardiac Autonomic Neuropathy in Type 2 Diabetes · Phase 4 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03448562 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by The First Affiliated Hospital with Nanjing Medical University
Last refreshed: 11 February 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03448562.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing