NCT03442738 (Endocuff) is a clinical trial of Endocuff group in Adenoma Detection Rate, sponsored by Universitätsklinikum Hamburg-Eppendorf.

Who is sponsoring NCT03442738?

NCT03442738 is sponsored by Universitätsklinikum Hamburg-Eppendorf.

What drugs are being tested in NCT03442738?

Interventions in NCT03442738: Endocuff group.

What condition does NCT03442738 study?

NCT03442738 studies Adenoma Detection Rate.

Is NCT03442738 still recruiting?

NCT03442738 is currently completed. Last updated 28 June 2023.

Last reviewed 2023-06-28 · How we verify

NCT03442738: Endocuff

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Prospective Randomized Comparison of the Adenoma Detection Rate With a Disposable Cap (ENDOCUFF VISION®)

Completed Last updated 28 June 2023

What this trial tests

trial testing Endocuff group in Adenoma Detection Rate in 1,382 participants. Completed in 30 September 2022.

Timeline

1 September 2017

Primary endpoint
30 September 2021

30 September 2022

Quick facts

Lead sponsor	Universitätsklinikum Hamburg-Eppendorf
Status	Completed
Study type	OBSERVATIONAL
Enrollment	1,382
Start date	1 September 2017
Primary completion	30 September 2021
Estimated completion	30 September 2022
Sites	9 locations across Germany

Drugs / interventions tested

Endocuff group

Conditions studied

Adenoma Detection Rate — all drugs for Adenoma Detection Rate →

Sponsor

Universitätsklinikum Hamburg-Eppendorf — full company profile →

Who can join

55 and older, any sex, with Adenoma Detection Rate. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to evaluate the effect of ENDOCUFF VISION® (caps with soft, about 1 cm long lateral feet of rubber ("Endocuff") to flatten the colon folds) on ADR in a real-life setting (general practices) and in a homogenous patient collective (screening colonoscopies only). It is a prospective randomized multi centric study, with participation of at least 10 study sites (private practice). The study is an inverstigator-initiated trial (IIT). Depending on the randomization (closed envelope), the patients are examined with the standard instruments without or with ENDOCUFF VISION®. Group 1: screening colonoscopy with standard colonoscopes with ENDOCUFF VISION® Group 2: screening colonoscopy with standard colonoscopes without cap

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Second-generation distal attachment cuff for adenoma detection in screening colonoscopy: a randomized multicenter study.
Zimmermann-Fraedrich K, Sehner S, Rösch T, Aschenbeck J, et al · · 2023 · cited 9× · PMID 36030888 · DOI 10.1016/j.gie.2022.08.030

Verify or expand the search:

Other recruiting trials for Adenoma Detection Rate

Currently open trials in the same condition.

NCT06961149 — Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate · NA · recruiting
NCT06678477 — Comparison of the Performance Between Conventional Colonoscopy and 3D Colonoscopy in Positive Fecal Immunochemical Test · NA · recruiting
NCT07076966 — Comparison of Adenoma Detection Rate in 3D vs. 2D Surveillance Colonoscopy · NA · recruiting
NCT05863208 — Artificial Intelligence-assisted Colonoscopy With or Without Endocuff Vision · NA · recruiting
NCT05125939 — Can Overall Adenoma Detection Rate Replace Screening Adenoma Detection Rate ? Multicenter Study · recruiting

Other Universitätsklinikum Hamburg-Eppendorf trials

Trials by the same sponsor.

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NCT07009522 — Hamburg Emotion Awareness and Regulation Group Training for Autistic Adolescents (HEART) · EARLY_PHASE1 · not yet recruiting
NCT07115394 — EEG Measurements to Capture DBS-induced Electric Potentials · recruiting
NCT06955884 — Patient Experience of Transoral Versus Transnasal Awake Tracheal Intubation · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03442738 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universitätsklinikum Hamburg-Eppendorf
Last refreshed: 28 June 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03442738.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing