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NCT03440996
Comparison of Three Toothpastes for the Prevention and Reduction of White Spot Lesions
NA trial testing Clinpro™ 5000 in White Spot Lesion in 90 participants. Completed in 30 December 2011.
30 June 2011
Quick facts
| Lead sponsor | University of Alabama at Birmingham |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 90 |
| Start date | 14 January 2011 |
| Primary completion | 30 June 2011 |
| Estimated completion | 30 December 2011 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Clinpro™ 5000
- Clinpro™ Tooth Crème
- MI-Paste Plus
Conditions studied
- White Spot Lesion — all drugs for White Spot Lesion →
- Orthodontic Treatment — all drugs for Orthodontic Treatment →
- Decalcification; Teeth — all drugs for Decalcification; Teeth →
Sponsor
University of Alabama at Birmingham
Who can join
Adults 12 to 60, any sex, with White Spot Lesion or Orthodontic Treatment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of the study is to determine if Clinpro™ 5000, Clinpro™ Tooth Crème, or MI-Paste Plus has an effect on the formation and resolution of white spot lesions for patients undergoing orthodontic treatment. This study will include 90 patients in the UAB Orthodontic Clinic.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of fluoride dentifrices on white spot lesions during orthodontic treatment: <i>A randomized trial</i>.
Kau CH, Wang J, Palombini A, Abou-Kheir N, et al · · 2019 · cited 19× · PMID 30719933 · DOI 10.2319/051818-371.1
Verify or expand the search:
- PubMed search for NCT03440996
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for White Spot Lesion
Currently open trials in the same condition.
- NCT07319884 — The Role of Fluoride Varnish Application in Preventing White Spot Lesions During Clear Aligner Treatment: A Controlled S · NA · active not recruiting
Other University of Alabama at Birmingham trials
Trials by the same sponsor.
- NCT04922229 — Comparative Effectiveness in the Management of Irreversible Pulpitis · NA · not yet recruiting
- NCT05060380 — Feasibility of a Novel Resistance Exercise in Individuals With Osteoporosis · NA · withdrawn
- NCT04768777 — Behavioral Intervention for Physical Activity and Sexual Dysfunction in Multiple Sclerosis · NA · not yet recruiting
- NCT06320951 — VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine · Phase 2 · not yet recruiting
- NCT07564934 — Leveraging Extended Reality Exergaming and Telehealth to Improve Physical Activity and Health in Children With Disabilit · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03440996 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Alabama at Birmingham
- Last refreshed: 22 February 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03440996.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing