NCT03438084 (INTER-CARDIO) is a NA clinical trial of Interesterified fat in Healthy Adults, sponsored by King's College London.

Who is sponsoring NCT03438084?

NCT03438084 is sponsored by King's College London.

What drugs are being tested in NCT03438084?

Interventions in NCT03438084: Interesterified fat, Non- interesterified fat, Rapeseed oil, Butter.

What condition does NCT03438084 study?

NCT03438084 studies Healthy Adults.

Is NCT03438084 still recruiting?

NCT03438084 is currently completed. Last updated 27 January 2020.

Last reviewed 2020-01-27 · How we verify

NCT03438084: INTER-CARDIO

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The INTER-CARDIO Study: The Impact of Commonly Consumed Fat on Cardiovascular Health; a Randomised Controlled Trial

Completed NA Last updated 27 January 2020

What this trial tests

NA trial testing Interesterified fat in Healthy Adults in 50 participants. Completed in 31 October 2019.

Timeline

1 July 2018

Primary endpoint
1 October 2019

31 October 2019

Quick facts

Lead sponsor	King's College London
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	prevention
Enrollment	50
Start date	1 July 2018
Primary completion	1 October 2019
Estimated completion	31 October 2019
Sites	2 locations across United Kingdom

Drugs / interventions tested

Interesterified fat
Non- interesterified fat
Rapeseed oil
Butter

Conditions studied

Healthy Adults — all drugs for Healthy Adults →

Sponsor

King's College London

Who can join

Adults 35 to 75, any sex, with Healthy Adults. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to investigate whether there are differences in postprandial cardiometabolic metabolic indices following interesterified fats used commercially versus application appropriate non- interesterifed alternative fat.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Postprandial lipid and vascular responses following consumption of a commercially-relevant interesterified palmitic acid-rich spread in comparison to functionally-equivalent non-interesterified spread and spreadable butter: a randomised controlled trial in healthy adults.
Hall WL, Alkoblan A, Gibson PS, D'Annibale M, et al · · 2024 · cited 7× · PMID 38380649 · DOI 10.1039/d3fo05324e
Impact of Postprandial Lipemia and Glycemia on Inflammatory Factors in over 1000 Individuals in the US and UK: Insights from the PREDICT 1 and InterCardio Studies
Berry S, Mazidi M, Franks P, Valdes A, et al · · 2020
No Difference in Lipemic Response or Endothelial Function Following Interesterified and Non-Interesterified Functionally Equivalent Fats: A Randomized Controlled Trial
Gibson P, D'Annibale M, Alkoblan A, Berry S, et al · · 2020

Verify or expand the search:

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Other King's College London trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03438084 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by King's College London
Last refreshed: 27 January 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03438084.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing