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NCT07518758: PolypOxy
Acute Effect of Polyphenols Supplementation on Endothelial Function and Exercise Related Markers, in Physically Active Healthy Volunteers.
NA trial testing Oral administration in Vasodilation in 38 participants. Participants enrolled and being followed up; not accepting new ones.
20 April 2026
Quick facts
| Lead sponsor | Nexira |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | triple |
| Primary purpose | other |
| Enrollment | 38 |
| Start date | 1 September 2025 |
| Primary completion | 20 April 2026 |
| Estimated completion | 27 April 2026 |
| Sites | 1 location across France |
Drugs / interventions tested
- Oral administration
Conditions studied
- Vasodilation — all drugs for Vasodilation →
- Exercise — all drugs for Exercise →
- Healthy Adults — all drugs for Healthy Adults →
Sponsor
Nexira
Who can join
Adults 35 to 55, any sex, with Vasodilation or Exercise. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To evaluate the effect of acute polyphenols supplementation on vasodilation and related markers along with exercise related markers (notably performance, respiratory exchanges, perceived exertion), before, during and after a hypoxic moderate-intensity exercise in healthy recreative volunteers.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07518758
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Vasodilation
Currently open trials in the same condition.
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- NCT05219799 — Sex Disparities in Hypoxic Vasodilation and Impact of Obesity · EARLY_PHASE1 · recruiting
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Other Nexira trials
Trials by the same sponsor.
- NCT06254209 — Study to Evaluate the Physiological Effects on the Skin of 3 Food Supplements Versus Placebo in 40-60 Years Old Female S · NA · completed
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07518758 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Nexira
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07518758.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing