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NCT03433144: TXA-OMFS
The Effects of Tranexamic Acid on Blood Loss During Orthognathic Surgery
Phase 4 trial testing Tranexamic Acid Injectable Solution in Tranexamic Acid. Withdrawn.
1 February 2019
Quick facts
| Lead sponsor | Nick Emanuele |
|---|---|
| Phase | Phase 4 |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Start date | 1 June 2018 |
| Primary completion | 1 February 2019 |
| Estimated completion | 6 July 2020 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Tranexamic Acid Injectable Solution — full drug profile →
- Placebo (normal saline 0.9%)
Conditions studied
- Tranexamic Acid — all drugs for Tranexamic Acid →
- Orthognathic Surgery — all drugs for Orthognathic Surgery →
Sponsor
Nick Emanuele
Who can join
Adults 16 to 65, any sex, with Tranexamic Acid or Orthognathic Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study seeks to answer the question: Does a single pre-operative dose of tranexamic acid have a statistically significant reduction in blood loss during orthognathic surgery? If it does, this drug may begin to be used routinely during orthognathic surgery to reduce blood loss in our patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03433144
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Tranexamic Acid Injectable Solution
Trials testing the same drug.
- NCT03923959 — Evaluation of TXA Prior to Surgery in the Geriatric Hip Fracture Population · Phase 3 · completed
- NCT03431805 — TRAnexamic Acid for Preventing Postpartum Hemorrhage Following a Cesarean Delivery · Phase 3 · completed
- NCT03101124 — Serum Concentration of Tranexamic Acid After Topical Administration in Massive Weight Loss Skin Reducing Surgery · Phase 2 · completed
Other recruiting trials for Tranexamic Acid
Currently open trials in the same condition.
- NCT07401394 — BAR-TAX - Tranexamic Acid in Bariatric Surgery. · NA · active not recruiting
- NCT07157631 — Efficacy and Safety of Tranexamic Acid in Adult Liver Transplantation---ESTA Trial · NA · recruiting
- NCT06657924 — Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03433144 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Nick Emanuele
- Last refreshed: 6 August 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03433144.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing