NCT03432546 (PAIN-ICU) is a clinical trial of Non-interventional in Critical Care, sponsored by Tampere University Hospital.

Who is sponsoring NCT03432546?

NCT03432546 is sponsored by Tampere University Hospital.

What drugs are being tested in NCT03432546?

Interventions in NCT03432546: Non-interventional.

What condition does NCT03432546 study?

NCT03432546 studies Critical Care, Acute Pain, Chronic Pain.

Is NCT03432546 still recruiting?

NCT03432546 is currently completed. Last updated 5 October 2022.

Last reviewed 2022-10-05 · How we verify

NCT03432546: PAIN-ICU

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Acute and Persistent Pain in ICU Patients

Completed Last updated 5 October 2022

What this trial tests

trial testing Non-interventional in Critical Care in 707 participants. Completed in 31 December 2021.

Timeline

6 April 2018

Primary endpoint
31 December 2021

31 December 2021

Quick facts

Lead sponsor	Tampere University Hospital
Status	Completed
Study type	OBSERVATIONAL
Enrollment	707
Start date	6 April 2018
Primary completion	31 December 2021
Estimated completion	31 December 2021
Sites	2 locations across Finland

Drugs / interventions tested

Non-interventional

Conditions studied

Critical Care — all drugs for Critical Care →
Acute Pain — all drugs for Acute Pain →
Chronic Pain — all drugs for Chronic Pain →

Sponsor

Tampere University Hospital

Who can join

18 and older, any sex, with Critical Care or Acute Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Approximately 20,000 patients are treated in intensive care units (ICU) in Finland annually. During ICU stay many diagnostic and other procedures as well as immobilization and underlying diseases may cause pain. Therefore the incidence of pain in ICU patients can be high. Acute pain may cause several detrimental effects including respiratory distress, tissue hypoxia, immunosuppression and anxiety. After discharge many survivors of critical care have lower health-related quality of life, symptoms of post-traumatic stress disorder or persistent pain. Only few studies with a focus on acute or persistent pain in ICU patients have been made, hence the incidence and risk factors for ICU-related pain is not very well known. Some of the identified risk factors for persisting pain may be increased age, sepsis or inadequate pain management during ICU stay. Opioids are most often used for analgesics in intensive care. Because they may have several adverse effects the use must be based on validated pain scales. Many factors such as sedation, relaxation or delirium of the patient complicates the management of the pain. This prospective observational study aims to determine the incidence and risk factors for acute and persistent pain in ICU patients as well as and the use of analgesics during intensive care.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

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Other Tampere University Hospital trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03432546 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Tampere University Hospital
Last refreshed: 5 October 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03432546.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing