NCT03431675 is a Phase 4 clinical trial of Ciprofloxacin in Meningitis, Meningococcal, sponsored by Epicentre.

Who is sponsoring NCT03431675?

NCT03431675 is sponsored by Epicentre.

What drugs are being tested in NCT03431675?

Interventions in NCT03431675: Ciprofloxacin.

What condition does NCT03431675 study?

NCT03431675 studies Meningitis, Meningococcal.

Is NCT03431675 still recruiting?

NCT03431675 is currently withdrawn. Last updated 14 August 2019.

Last reviewed 2019-08-14 · How we verify

NCT03431675

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ciprofloxacin for the Prevention of Meningococcal Meningitis 2018

Withdrawn Phase 4 Last updated 14 August 2019

What this trial tests

Phase 4 trial testing Ciprofloxacin in Meningitis, Meningococcal. Withdrawn.

Timeline

1 March 2019

Primary endpoint
30 June 2019

31 December 2019

Quick facts

Lead sponsor	Epicentre
Phase	Phase 4
Status	Withdrawn
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Start date	1 March 2019
Primary completion	30 June 2019
Estimated completion	31 December 2019
Sites	1 location across Niger

Drugs / interventions tested

Ciprofloxacin (Ciprofloxacin) — full drug profile →

Conditions studied

Meningitis, Meningococcal — all drugs for Meningitis, Meningococcal →

Sponsor

Epicentre — full company profile →

Who can join

Eligibility, any sex, with Meningitis, Meningococcal. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The trial is an interventional, cluster-randomized trial to assess the impact of oral ciprofloxacin for household and community contacts of meningitis cases on the incidence of meningitis during an epidemic. The trial contains a nested sub-study ("resistance study") to assess the effect of a single dose of ciprofloxacin on the prevalence of fluoroquinolone-resistant enterobacteriaceae in the study area.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Ciprofloxacin

Trials testing the same drug.

NCT07492134 — APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis) · Phase 2 · not yet recruiting
NCT07016165 — Ciprofloxacin vs Ceftazidime for Empirical Treatment of High-Risk Neutropenic Fever in Children With Hematologic Maligna · Phase 4 · recruiting
NCT04791579 — Antibiotic Prophylaxis for Neurogenic Bladder Botox · Phase 2 · recruiting
NCT05846399 — CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE) · Phase 4 · recruiting
NCT05844735 — A Randomized Placebo- and Active Comparator-controlled Study to Evaluate the Photosafety of SAR441566 · Phase 1 · completed

Other recruiting trials for Meningitis, Meningococcal

Currently open trials in the same condition.

NCT06113198 — A Study on the Immune Response and Safety of a Vaccine Against N. Meningitidis Serogroup B Infection in Healthy Infants · Phase 4 · active not recruiting
NCT05087056 — Safety, Tolerability, and Immunogenicity of MenABCWY Administered on Different Dosing Schedules in Healthy Adolescents · Phase 2 · active not recruiting

Other Epicentre trials

Trials by the same sponsor.

NCT06382857 — Effectiveness of a Microbiome-directed Food to Promote Programmatic and Sustained Nutritional Recovery Among Children Wi · NA · recruiting
NCT05551819 — Acceptability of a Microbiome-directed Food in Young Children With Acute Malnutrition · NA · completed
NCT07506213 — Development, Feasibility and Acceptability of Recipes for Locally Available, Specially Formulated Foods for the Manageme · NA · completed
NCT05453253 — Immune Response to a Delayed Second Dose of Oral Cholera Vaccine · Phase 4 · unknown
NCT05449717 — Incidence of Relapse and Post-Kala-Azar Dermal Leishmaniasis in South Sudan · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03431675 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Epicentre
Last refreshed: 14 August 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03431675.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing